A comparison of InVivoStat with other statistical software packages for analysis of data generated from animal experiments
Open accessAbstract
InVivoStat is a free-to-use statistical software package for analysis of data generated from animal experiments. The package is designed specifically for researchers in the behavioural sciences, where exploiting the experimental design is crucial for reliable statistical analyses. This paper compares the analysis of three experiments conducted using InVivoStat with other widely used statistical packages: SPSS (V19), PRISM (V5), UniStat (V5.6) and Statistica (V9). We show that InVivoStat provides results that are similar to those from the other packages and, in some cases, are more advanced. This investigation provides evidence of further validation of InVivoStat and should strengthen users’ confidence in this new software package.
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The number of animals and group sizes were calculated using InVivoStat.
“We calculated the number of animals and group sizes to be used via InVivoStat, an R-based statistical package [26].”
From Pharmacological ablation of astrocytes reduces Aβ degradation and synaptic connectivity in an ex vivo model of Alzheimer’s disease (2021) · cites this paper as [26]
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Davis, N., Mota, B. C., Stead, L., Palmer, E. O. C., Lombardero, L., Rodríguez-Puertas, R., de Paola, V., Barnes, S. J., & Sastre, M. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02117-y · Cited by 65 · see citing works
Andreasen, J. T., Redrobe, J. P., Nielsen, E. Ø., Christensen, J. K., Olsen, G. M., & Peters, D. (2013) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.04.060 · Cited by 15 · see citing works
- Authors
- Clark, R. A., Shoaib, M., Hewitt, K. N., Stanford, S. C., & Bate, S. T.
- Affiliations
- Huntingdon Life Sciences Ltd, Huntingdon, UK
- Newcastle University (GB)
- University of Oxford (GB)
- University College London (GB)
- Venue
- Journal of Psychopharmacology
- Publisher
- SAGE Publications
- Published
- 2011-11-08
- Volume
- 26
- Issue
- 8
- Pages
- 1136-1142
- ISSN
- 0269-8811 (ISSN-L)
- 1461-7285
- OpenAlex
- W2057430366
- Cited by
- 122
- References
- 0
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 8 · 2023: 6 · 2022: 5 · 2021: 11 · 2020: 10 · 2019: 5 · 2018: 10 · 2017: 8 · 2016: 15 · 2015: 10 · 2014: 11 · 2013: 7 · 2012: 6
- FWCI
- 11.02
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Locations
- Journal of Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- Topics
- Health Sciences › Veterinary › Small Animals › Animal testing and alternatives
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Applications
- Keywords
- statistical software comparison, animal experimentation, behavioral science, experimental design, SPSS, PRISM, STATISTICA, software validation, psychopharmacology
- MeSH terms
- Animals, Behavioral Sciences, Biometry, Mathematical Computing, Research Design, Animal Experimentation, Rats
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