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Disability, HRQoL and resource use among chronic and episodic migraineurs: Results from the International Burden of Migraine Study (IBMS)
Abstract
Background: Migraine imposes significant burden on patients, their families and health care systems. In this study, we compared episodic to chronic migraine sufferers to determine if migraine status predicted headache-related disability, health-related quality of life (HRQoL) and health care resource utilization. Methods: A Web-based survey was administered to panelists from nine countries. Participants were classified as having chronic migraine (CM), episodic migraine (EM) or neither using a validated questionnaire. Data collected and then analyzed included sociodemographics, clinical characteristics, Migraine Disability Assessment, Migraine-Specific Quality of Life v2.1, Patient Health Questionnaire and health care resource utilization. Findings: Of the respondents, 5.7% had CM and 94.3% had EM, with CM patients reporting significantly more severe disability, lower HRQoL, higher levels of anxiety and depression and greater health care resource utilization compared to those with EM. Interpretation: These results provide evidence that will enhance our understanding of the factors driving health care costs and will contribute to development of cost-effective health care strategies.
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“However, the current understanding of migraine burden among individuals with the highest unmet needs, specifically those experiencing ≥4 monthly migraine days (MMDs) and prior prophylaxis failure, is limited.”
From My Migraine Voice survey: a global study of disease burden among individuals with migraine for whom preventive treatments have failed (2018) · cites this paper as [7]
In the citing paper
“Specifically, no detailed assessment of the current treatment pathway, impact on work productivity, or burden associated with premonitory and postdromal phases of migraine is available in individuals experiencing ≥4 MMDs who have had previous prophylactic treatments that failed and continue to experience frequent migraines.”
From My Migraine Voice survey: a global study of disease burden among individuals with migraine for whom preventive treatments have failed (2018) · cites this paper as [7]
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Metadata
- Authors
- Blumenfeld, A., Varon, S., Wilcox, T., Buse, D., Kawata, A., Manack, A., Goadsby, P., & Lipton, R.
- Affiliations
- The Neurology Center, USA.
- Allergan (United States) (US)
- United BioSource Corporation, USA.
- Albert Einstein College of Medicine (US)
- University of California, USA.
- Montefiore Headache Center and Albert Einstein College of Medicine, USA.
- Corresponding author
- Blumenfeld, AM
- Venue
- Cephalalgia
- Publisher
- SAGE Publications
- Published
- 2010-09-02
- Volume
- 31
- Issue
- 3
- Pages
- 301-315
- ISSN
- 0333-1024 (ISSN-L)
- 1468-2982
- OpenAlex
- W2142670324
- Cited by
- 627
- References
- 50
- Citations by year
- 2026: 22 · 2025: 34 · 2024: 53 · 2023: 50 · 2022: 41 · 2021: 58 · 2020: 79 · 2019: 49 · 2018: 39 · 2017: 25 · 2016: 34 · 2015: 38 · 2014: 26 · 2013: 27 · 2012: 38
- FWCI
- 16.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cephalalgia (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Migraine and Headache Studies
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Keywords
- chronic migraine, episodic migraine, headache-related disability, health-related quality of life, healthcare resource utilization, anxiety, depression, health care costs
- MeSH terms
- Adult, Chronic Disease, Cross-Sectional Studies, Data Collection, Disability Evaluation, Female, Health Resources, Humans, Male, Migraine Disorders, Online Systems, Quality of Life, Cost of Illness
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