Guidelines of the International Headache Society for controlled trials of preventive treatment of chronic migraine in adults
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Background Quality clinical trials form an essential part of the evidence base for the treatment of headache disorders. In 1991, the International Headache Society Clinical Trials Standing Committee developed and published the first edition of the Guidelines for Controlled Trials of Drugs in Migraine. In 2008, the Committee published the first specific guidelines on chronic migraine. Subsequent advances in drug, device, and biologicals development, as well as novel trial designs, have created a need for a revision of the chronic migraine guidelines. Objective The present update is intended to optimize the design of controlled trials of preventive treatment of chronic migraine in adults, and its recommendations do not apply to trials in children or adolescents.
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The study did not present detailed findings from the monthly perspective diary data (frequency of headache and systematic assessments of headache parameters) as recommended by guidelines for migraine headache trials.
“Also, this study did not present detail findings from the monthly perspective diary data (frequency of headache and systematic assessments of headache parameters) as recommended by guidelines for migraine headache trials.73”
From Acceptance and Commitment Therapy for Primary Headache Sufferers: A Randomized Controlled Trial of Efficacy (2021) · cites this paper as [73]
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References 68 · Cited by 388
- Authors
- Tassorelli, C., Diener, H.-C., Dodick, D. W., Silberstein, S. D., Lipton, R. B., Ashina, M., Becker, W. J., Ferrari, M. D., Goadsby, P. J., Pozo-Rosich, P., Wang, S.-J., & for the International Headache Society Clinical Trials Standing Committee
- Affiliations
- University of Pavia (IT)
- Essen University Hospital (DE)
- Mayo Clinic (US)
- Thomas Jefferson University (US)
- Albert Einstein College of Medicine (US)
- University of Copenhagen (DK)
- University of Calgary (CA)
- Leiden University Medical Center (NL)
- National Institute for Health and Care Research (GB)
- Headache Research Group, VHIR, Universitat Autònoma de Barcelona, Barcelona Spain
- Taipei Veterans General Hospital (TW)
- Corresponding author
- Tassorelli, Cristina
- Diener, Hans-Christoph
- ORCID
- Venue
- Cephalalgia
- Publisher
- SAGE Publications
- Published
- 2018-03-04
- Volume
- 38
- Issue
- 5
- Pages
- 815-832
- ISSN
- 0333-1024 (ISSN-L)
- 1468-2982
- OpenAlex
- W2793051137
- Cited by
- 388
- References
- 68
- Citations by year
- 2026: 37 · 2025: 50 · 2024: 48 · 2023: 59 · 2022: 59 · 2021: 58 · 2020: 50 · 2019: 20 · 2018: 6 · 2017: 1
- FWCI
- 26.36
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Cephalalgia (publishedVersion)
- PubMed (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Leiden Repository (Leiden University) (submittedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Funders
- National Institute for Health and Care Research (NF-SI-0616-10031)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Migraine and Headache Studies
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
- Keywords
- chronic migraine, migraine prophylaxis, trial design, prophylaxis, adults, drug development, biologicals, headache disorders
- MeSH terms
- Prescription Drug Overuse, Adult, Anxiety, Clinical Protocols, Depression, Double-Blind Method, Female, Health Surveys, Humans, Male, Migraine Disorders, Quality of Life, Sex Factors, Age of Onset, Cross-Over Studies, Controlled Clinical Trials as Topic, Endpoint Determination, Secondary Prevention, Young Adult, Chronic Pain
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