Antecedent Biomarkers of Alzheimer’s Disease: The Adult Children Study
Abstract
The Washington University Adult Children Study is a longitudinal study to develop and validate biological markers, imaging features, and other indicators of preclinical Alzheimer’s disease to aid in identifying individuals at high risk for developing symptomatic Alzheimer’s disease. Two groups of participants between the ages of 45 and 74 are being enrolled in the Adult Children Study. Group 1 represents adult children who have at least 1 parent with Alzheimer’s disease. Group 2 represents adult children whose parents have lived at least to age 70 without dementia. The Adult Children Study participants have been highly motivated to participate, and this study will require the investment of many years from the participants and the investigators before its most significant results will be known.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
OASIS-3 includes participants enrolled into several ongoing studies through the Knight ADRC at Washington University in St. Louis spanning over 15 years and several research studies - Memory and Aging Project, Adult Children Study, and Healthy Aging and Senile Dementia.
“OASIS-3 includes participants enrolled into several ongoing studies through the Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight ADRC) at Washington University in St. Louis spanning over 15 years and several research studies - Memory and Aging Project, Adult Children Study 14 , and Healthy Aging and Senile Dementia.”
From OASIS-3: Longitudinal Neuroimaging, Clinical, and Cognitive Dataset for Normal Aging and Alzheimer Disease (2019) · cites this paper as [14]
The citation lists haven’t been fetched yet
References 14 · Cited by 44
- Authors
- Coats, M., & Morris, J. C.
- Affiliations
- Washington University in St. Louis (US)
- ORCID
- Morris, John C.
- Venue
- Journal of Geriatric Psychiatry and Neurology
- Publisher
- SAGE Publications
- Published
- 2005-12
- Volume
- 18
- Issue
- 4
- Pages
- 242-244
- ISSN
- 0891-9887 (ISSN-L)
- 1552-5708
- OpenAlex
- W2043905483
- Cited by
- 44
- References
- 14
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 2 · 2020: 3 · 2019: 4 · 2018: 2 · 2017: 5 · 2016: 3 · 2015: 1 · 2014: 1 · 2013: 1
- FWCI
- 1.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Geriatric Psychiatry and Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cancer-related cognitive impairment studies
- Keywords
- Alzheimer's disease, preclinical Alzheimer's disease, biomarkers, familial risk, high-risk identification, neuroimaging, longitudinal cohort
- MeSH terms
- Aged, Alzheimer Disease, Diagnosis, Differential, Female, Humans, Longitudinal Studies, Male, Middle Aged, Pedigree, Risk Factors, Biomarkers, Genetic Predisposition to Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
