Cited by 297Reproductive tract infections researchGynecological conditions and treatmentsCervical Cancer and HPV Research

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2018 European (IUSTI/WHO) International Union against sexually transmitted infections (IUSTI) World Health Organisation (WHO) guideline on the management of vaginal discharge

Sherrard, Jackie, Wilson, Janet, Donders, Gilbert, Mendling, Werner, Jensen, Jørgen S·2018·International Journal of STD & AIDS

DOI 10.1177/0956462418785451

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Abstract

Four common pathological conditions are associated with vaginal discharge: bacterial vaginosis, aerobic vaginitis, candidosis, and the sexually transmitted infection, trichomoniasis. Chlamydial or gonococcal cervical infection may result in vaginal discharge. Vaginal discharge may be caused by a range of other physiological and pathological conditions including atrophic vaginitis, desquamative inflammatory vaginitis, cervicitis, and mucoid ectopy. Psychosexual problems may present with recurrent episodes of vaginal discharge and vulval burning. These need to be considered if tests for specific infections are negative. Many of the symptoms and signs are non-specific and a number of women may have other conditions such as vulval dermatoses or allergic and irritant reactions.

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Reliability of diagnosing bacterial vaginosis is improved by a standardized method of gram stain interpretation
Nugent, R. P., Krohn, M. A., & Hillier, S. L. (1991) · Journal of Clinical Microbiology · doi:10.1128/jcm.29.2.297-301.1991 · Cited by 3,332
Nonspecific vaginitis
Amsel, R., Totten, P. A., Spiegel, C. A., Chen, K. C. S., Eschenbach, D. A., & Holmes, K. K. (1983) · The American Journal of Medicine · doi:10.1016/0002-9343(83)91112-9 · Cited by 2,412
Molecular Identification of Bacteria Associated with Bacterial Vaginosis
Fredricks, D. N., Fiedler, T. L., & Marrazzo, J. M. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043802 · Cited by 1,303
Non-ulcerative sexually transmitted diseases as risk factors for HIV-1 transmission in women
Laga, M., Manoka, A. T., Kivuvu, M., Malele, B., Tuliza, M., Nzila, N., Goeman, J., Behets, F., Batter, V., Alary, M., et al. (1993) · AIDS · doi:10.1097/00002030-199301000-00015 · Cited by 1,139
Trichomonas vaginalis Associated With Low Birth Weight and Preterm Delivery
COTCH, M. F., PASTOREK, J. G., NUGENT, R. P., HILLIER, S. L., GIBBS, R. S., MARTIN, D. H., ESCHENBACH, D. A., EDELMAN, R., CAREY, C. J., REGAN, J. A., et al. (1997) · Sexually Transmitted Diseases · doi:10.1097/00007435-199707000-00008 · Cited by 836
High Recurrence Rates of Bacterial Vaginosis over the Course of 12 Months after Oral Metronidazole Therapy and Factors Associated with Recurrence
Bradshaw, C. S., Morton, A. N., Hocking, J. S., Garland, S. M., Morris, M. B., Moss, L. M., Horvath, L. B., Kuzevska, I., & Fairley, C. K. (2006) · The Journal of Infectious Diseases · doi:10.1086/503780 · Cited by 793
The prevalence of bacterial vaginosis in the United States, 2001–2004; associations with symptoms, sexual behaviors, and reproductive health.
Koumans, E. H., Sternberg, M., Bruce, C., McQuillan, G., Kendrick, J., Sutton, M., & Markowitz, L. E. (2007) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e318074e565 · Cited by 761
Bacterial vaginosis as a risk factor for preterm delivery: A meta-analysis
Leitich, H., Bodner‐Adler, B., Brunbauer, M., Kaider, A., Egarter, C., & Husslein, P. W. (2003) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2003.339 · Cited by 735
Bacterial vaginosis and HIV acquisition: A meta-analysis of published studies
Atashili, J., Poole, C., Ndumbe, P. M., Adimora, A. A., & Smith, J. S. (2008) · AIDS · doi:10.1097/qad.0b013e3283021a37 · Cited by 706
Antibiotics for treating bacterial vaginosis in pregnancy
Brocklehurst, P., Gordon, A., Heatley, E., & Milan, S. J. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000262.pub4 · Cited by 609

Show all 110 references

Research works printed but not linked: 18

French JI, 1999, Obstet Gynecol, 93, 715
Gülmezoglu AM, 2011, Cochrane Database Syst Rev, 5, CD000220
Eckert LO, 1998, Obstet Gynecol, 92, 757
10.1111/j.1471-0528.2002.00432.x · DOI
Hopwood V, 1988, Genitourin Med, 64, 331
Priestley CJ, 1997, Genitourin Med, 73, 23
Borchardt KA, 1997, Genitourin Med, 73, 297
el Naga IF, 2001, J Egypt Soc Parasitol, 31, 647
Senok AC, 2009, Cochrane Database Syst Rev, 4, CD006289
Nurbhai M, 2007, Cochrane Database Syst Rev, 4, CD002845
Cooke G, 2011, Cochrane Database Syst Rev, 5, CD009151
2008, Am J Obstet Gynecol, 199, 613
Dennerstein GJ., 1986, J Reprod Med, 31, 801
Forna F, 2003, Cochrane Database Syst Rev, 2, CD000218
Thin RN, 1979, Br J Vener Dis, 55, 354
Gülmezoglu AM, 2011, Cochrane Database Syst Rev, 5, CD000220
Amaya-Guio J, 2016, Cochrane Database Syst Rev, 10, CD011701
Fong IW., 1992, Genitourin Med, 68, 174

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Authors: Sherrard, J., Wilson, J., Donders, G., Mendling, W., & Jensen, J. S.
Affiliations: Buckinghamshire Healthcare NHS Trust (GB)
Leeds Teaching Hospitals NHS Trust (GB)
Antwerp University Hospital (BE)
Infektionen in Gynäkologie und Geburtshilfe, Wuppertal, Germany
Statens Serum Institut (DK)
Corresponding author: Sherrard, Jackie
Jensen, Jørgen S
ORCID: Sherrard, Jackie
Wilson, Janet
Donders, Gilbert
Mendling, Werner
Jensen, Jørgen S
Venue: International Journal of STD & AIDS
Publisher: SAGE Publications
Published: 2018-07-27
Volume: 29
Issue: 13
Pages: 1258-1272
ISSN: 0956-4624 (ISSN-L)
1758-1052
DOI: 10.1177/0956462418785451
OpenAlex: W2882984619
Cited by: 297
References: 110
Citations by year: 2026: 20 · 2025: 25 · 2024: 39 · 2023: 50 · 2022: 60 · 2021: 42 · 2020: 38 · 2019: 21 · 2018: 1
FWCI: 20.61
Type: journal article
Language: en
Open access: closed
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: International Journal of STD & AIDS (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
Keywords: vaginal discharge, bacterial vaginosis, aerobic vaginitis, vaginal candidiasis, trichomoniasis, chlamydia, gonorrhea, vaginal atrophy, desquamative inflammatory vaginitis, cervicitis, psychosexual problems, sexually transmitted infections, clinical management
MeSH terms: Europe, Female, Humans, Sexually Transmitted Diseases, Trichomonas Infections, Vaginitis, World Health Organization, Vaginosis, Bacterial, Guidelines as Topic, Vaginal Discharge

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2018 European (IUSTI/WHO) International Union against sexually transmitted infections (IUSTI) World Health Organisation (WHO) guideline on the management of vaginal discharge

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