Postural Orthostatic Tachycardia Syndrome (POTS) – A novel member of the autoimmune family
Open accessAbstract
Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous disorder of the autonomic nervous system in which a change from the supine position to an upright position causes an abnormally large increase in heart rate or tachycardia (30 bpm within 10 min of standing or head-up tilt). This response is accompanied by a decrease in blood flow to the brain and hence a spectrum of symptoms associated with cerebral hypoperfusion. Many of these POTS-related symptoms are also observed in chronic anxiety and panic disorders, and therefore POTS is frequently under- and misdiagnosed.
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Blitshteyn determined a high prevalence of positive ANA and other autoantibodies and a high prevalence of comorbid autoimmune disorders in patients with POTS.
“Blitshteyn recently determined the high prevalence of positive ANA and other autoantibodies and the high prevalence of comorbid autoimmune disorders that exist in patients with POTS.8,9”
From Autoimmune postural orthostatic tachycardia syndrome (2018) · cites this paper as [9]
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References 44 · Cited by 55
- Authors
- Dahan, S., Tomljenovic, L., & Shoenfeld, Y.
- Affiliations
- Tel Aviv University (IL)
- University of British Columbia (CA)
- Corresponding author
- Shoenfeld, Y
- Venue
- Lupus
- Publisher
- SAGE Publications
- Published
- 2016-02-03
- Volume
- 25
- Issue
- 4
- Pages
- 339-342
- ISSN
- 0961-2033 (ISSN-L)
- 1477-0962
- OpenAlex
- W2286198476
- Cited by
- 55
- References
- 44
- Citations by year
- 2026: 2 · 2024: 6 · 2023: 2 · 2022: 7 · 2021: 5 · 2020: 6 · 2019: 3 · 2018: 14 · 2017: 4 · 2016: 6
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Lupus (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- postural orthostatic tachycardia syndrome, autonomic dysfunction, autoimmune disease, cerebral hypoperfusion, tachycardia, misdiagnosis, chronic anxiety, panic disorder, head-up tilt
- MeSH terms
- Autoimmune Diseases, Cerebrovascular Circulation, Cross Reactions, Heart Rate, Humans, Oncogene Proteins, Viral, Risk Factors, Autoimmunity, Supine Position, Death, Sudden, Cardiac, Capsid Proteins, Papillomavirus Vaccines, Postural Orthostatic Tachycardia Syndrome
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