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The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Sensitivity and specificity of the ankle—brachial index to diagnose peripheral artery disease: a structured review

Open access
Dachun Xu, Jue Li, Liling Zou, Yawei Xu, Dayi Hu, Pagoto, Sherry L, Yunsheng Ma·2010·Vascular Medicine

Abstract

The ankle—brachial index (ABI) is a simple, inexpensive diagnostic test for peripheral artery disease (PAD). However, it has shown variable accuracy for identification of significant stenosis. The authors performed a structured review of the sensitivity and specificity of ABI ≤ 0.90 for the diagnosis of PAD. MEDLINE, EMBASE, Cochrane databases, Science Citation Index database, and Biological Abstracts database were searched for studies of the sensitivity and specificity of using ABI ≤ 0.90 for the diagnosis of PAD. Eight studies comprising 2043 patients (or limbs) met the inclusion criteria. The result indicated that, although strict inclusion criteria on studies were formulated, different reference standards were found in these studies, and methods of ABI determination and characteristics of populations varied greatly. A high level of specificity (83.3—99.0%) and accuracy (72.1—89.2%) was reported for an ABI ≤ 0.90 in detecting ≥ 50% stenosis, but there were different levels of sensitivity (15—79%). Sensitivity was low, especially in elderly individuals and patients with diabetes. In conclusion, the test of ABI ≤ 0.90 can be a simple and useful tool to identify PAD with serious stenosis, and may be substituted for other non-invasive tests in clinical practice.

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Metadata

Authors
Xu, D., Li, J., Zou, L., Xu, Y., Hu, D., Pagoto, S. L., & Ma, Y.
Venue
Vascular Medicine
Published
2010-10
Volume
15
Issue
5
Pages
361-369
ISSN
  • 1358-863X (ISSN-L)
  • 1477-0377
OpenAlex
W2154443303
Cited by
302
References
3
FWCI
12.73
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Sensitivity and specificity of the ankle—brachial index to diagnose peripheral artery disease: a structured review. https://app.cochat.ai/papers/10.1177/1358863x10378376
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Xu, D., Li, J., Zou, L., Xu, Y., Hu, D., Pagoto, S. L., & Ma, Y. (2010). Sensitivity and specificity of the ankle—brachial index to diagnose peripheral artery disease: a structured review. Vascular Medicine. https://doi.org/10.1177/1358863x10378376

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.