The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The role of general practitioners in the diagnosis and treatment of Alzheimer’s disease: a multinational survey
Abstract
Alzheimer's disease (AD) is a growing healthcare problem. Early diagnosis and effective treatment would benefit patients and caregivers, as well as having economic implications. We conducted a survey of 741 caregivers of patients with AD in Australia, France, Italy, Spain and the UK to assess the current situation regarding the diagnosis and treatment of AD in routine clinical practice. The average time from when symptoms were first noticed by the caregiver to making the first doctor's appointment was 4 months, but 22% of caregivers waited more than 1 year before consulting a doctor. Although the majority of patients (74%) consulted their general practitioner first, the diagnosis was more likely to be made by a specialist; on average, there was a 1-year delay from when symptoms were first noticed by the caregiver to diagnosis. Access to AD care is restricted by many national healthcare systems. The delay in diagnosis imposed by such restrictions impacts on access to early and effective treatment.
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Some bias due to prescriptions for prodromal symptoms occurring more than 5 years before diagnosis may remain because some early symptoms such as cognitive decline and depression can start to emerge up to 10 years before diagnosis.
“Some bias due to prescriptions for prodromal symptoms occurring more than 5 years before diagnosis may remain because, while there is an average of 1 to 5 years between onset of symptoms and dementia diagnosis,37,38 some early symptoms such as cognitive decline and depression can start to emerge up to 10 years before diagnosis.39,40”
From Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study (2019) · cites this paper as [37]
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Cites
The cholinergic hypothesis of Alzheimer’s disease: A review of progress
Francis, P. T., Palmer, A. M., Snape, M., & Wilcock, G. K. (1999) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.66.2.137 · Cited by 2,198
Farlow, M., Anand, R., Messina Jr, J., Hartman, R., & Veach, J. (2000) · European Neurology · doi:10.1159/000008243 · Cited by 332
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Research works printed but not linked: 25
- 10.1111/j.1600-0404.1996.tb00382.x · DOI
- 10.1159/000110922 · DOI
- Lobo A, 2000, Neurology, 54, S4, 10.1212/WNL.54.1.4 · DOI
- Fratiglioni L, 2000, Neurology, 54, S10
- 10.1017/S1461145700001905 · DOI · Paper page
- 10.1001/archinte.158.9.1021 · DOI
- 10.1212/WNL.50.1.136 · DOI · Paper page
- 10.1159/000017126 · DOI
- Rogers SL, 1996, Dementia, 7, 293
- 10.1212/WNL.57.3.489 · DOI
- 10.1136/bmj.318.7184.633 · DOI · Paper page
- 10.1212/WNL.54.12.2261 · DOI
- 10.1212/WNL.54.12.2269 · DOI
- 10.1212/WNL.57.4.613 · DOI
- 10.1046/j.1365-2389.2003.51260.x · DOI
- 10.1016/S0278-5846(01)00326-8 · DOI
- Wilkinson DG, 2002, Int J Clin Pract, 56, 509, 10.1111/j.1742-1241.2002.tb11310.x · DOI
- 10.1017/S1041610200006499 · DOI
- 10.2165/00002512-200320100-00006 · DOI
- 10.1159/000068786 · DOI
- Winblad B, 1999, Alzheimer Dis Assoc Disord, 13, S9
- 10.1377/hlthaff.17.6.206 · DOI
- 10.1159/000066669 · DOI
- 10.1046/j.1365-2389.2003.51306.x · DOI
- National Institute for Clinical Excellence., 2001, Drugs for Alzheimer's Disease — Full Guidance.
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Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study
Coupland, C. A. C., Hill, T., Dening, T., Morriss, R., Moore, M., & Hippisley-Cox, J. (2019) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2019.0677 · Cited by 637
Luck, T., Luppa, M., Sieber, J., Schomerus, G., Werner, P., König, H.-H., & Riedel-Heller, S. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050792 · Cited by 67
Hong, B., Bea, S., Ko, H. Y., Kim, W. J., Cho, Y. M., & Shin, J.-Y. (2024) · Annals of Internal Medicine · doi:10.7326/m23-3220 · Cited by 33
Veneziani, F., Panza, F., Solfrizzi, V., Capozzo, R., Barulli, M. R., Leo, A., Lozupone, M., Fontana, A., Arcuti, S., Copetti, M., et al. (2016) · International Psychogeriatrics · doi:10.1017/s1041610216000041 · Cited by 27
Metadata
- Authors
- Wilkinson, D., Stave, C., Keohane, D., & Vincenzino, O.
- Affiliations
- Memory Assessment and Research Centre, Southampton, UK
- Pfizer (United States) (US)
- Corresponding author
- Wilkinson, D
- Venue
- Journal of International Medical Research
- Publisher
- SAGE Publications
- Published
- 2004-04
- Volume
- 32
- Issue
- 2
- Pages
- 149-159
- ISSN
- 0300-0605 (ISSN-L)
- 1473-2300
- OpenAlex
- W1965904633
- Cited by
- 99
- References
- 2
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 3 · 2023: 2 · 2022: 4 · 2021: 4 · 2020: 5 · 2019: 7 · 2018: 5 · 2017: 2 · 2016: 3 · 2015: 5 · 2014: 5 · 2013: 6 · 2012: 6
- FWCI
- 2.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of International Medical Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- Alzheimer's disease, general practitioners, early diagnosis, delayed diagnosis, health care access, specialist referral, health system barriers, primary care, cross-national comparison
- MeSH terms
- Alzheimer Disease, Data Collection, Humans, Physician's Role, Physicians, Family, Caregivers
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