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Efficacy of Silver Diamine Fluoride for Caries Reduction in Primary Teeth and First Permanent Molars of Schoolchildren: 36-month Clinical Trial
Abstract
We hypothesized that the six-monthly application of silver diamine fluoride (SDF) can arrest the development of caries in the deciduous dentition of six-year-old schoolchildren and prevent caries in their first permanent molars. A prospective controlled clinical trial was conducted on the efficacy of a 38% SDF solution for caries reduction. Four hundred and twenty-five six-year-old children were divided into two groups: One group received SDF solution in primary canines and molars and first permanent molars every 6 mos for 36 mos. The second group served as controls. The 36-month follow-up was completed by 373 children. The mean number of new decayed surfaces appearing in primary teeth during the study was 0.29 in the SDF group vs. 1.43 in controls. The mean of new decayed surfaces in first permanent molars was 0.37 in the SDF group vs. 1.06 in controls. The SDF solution was found to be effective for caries reduction in primary teeth and first permanent molars in schoolchildren.
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Cited by
Minimal intervention dentistry for managing dental caries – a review
Frencken, J. E., Peters, M. C., Manton, D. J., Leal, S. C., Gordan, V. V., & Eden, E. (2012) · International Dental Journal · doi:10.1111/idj.12007 · Cited by 531
UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent
Horst, J. A., Ellenikiotis, H., & Milgrom, P. L. (2016) · Journal of the California Dental Association · doi:10.1080/19424396.2016.12220962 · Cited by 426
Mechanisms of silver diamine fluoride on arresting caries: a literature review
Zhao, I. S., Gao, S. S., Hiraishi, N., Burrow, M. F., Duangthip, D., Mei, M. L., Lo, E. C.-M., & Chu, C.-H. (2018) · International Dental Journal · doi:10.1111/idj.12320 · Cited by 365
Topical fluoride for caries prevention
Weyant, R. J., Tracy, S. L., Anselmo, T. (., Beltrán-Aguilar, E. D., Donly, K. J., Frese, W. A., Hujoel, P. P., Iafolla, T., Kohn, W., Kumar, J., et al. (2013) · The Journal of the American Dental Association · doi:10.14219/jada.archive.2013.0057 · Cited by 357
Evidence-based clinical practice guideline on nonrestorative treatments for carious lesions
Slayton, R. L., Urquhart, O., Araujo, M. W. B., Fontana, M., Guzmán-Armstrong, S., Nascimento, M. M., Nový, B. B., Tinanoff, N., Weyant, R. J., Wolff, M. S., et al. (2018) · The Journal of the American Dental Association · doi:10.1016/j.adaj.2018.07.002 · Cited by 317
Metadata
- Authors
- Llodra, J. C., Rodriguez, A., Ferrer, B., Menardia, V., Ramos, T., & Morato, M.
- Venue
- Journal of Dental Research
- Publisher
- SAGE Publications
- Published
- 2005-08
- Volume
- 84
- Issue
- 8
- Pages
- 721-724
- ISSN
- 0022-0345 (ISSN-L)
- 1544-0591
- OpenAlex
- W2123281000
- Cited by
- 358
- References
- 0
- FWCI
- 2.40
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Efficacy of Silver Diamine Fluoride for Caries Reduction in Primary Teeth and First Permanent Molars of Schoolchildren: 36-month Clinical Trial. https://app.cochat.ai/papers/10.1177/154405910508400807
- The paper
- Llodra, J. C., Rodriguez, A., Ferrer, B., Menardia, V., Ramos, T., & Morato, M. (2005). Efficacy of Silver Diamine Fluoride for Caries Reduction in Primary Teeth and First Permanent Molars of Schoolchildren: 36-month Clinical Trial. Journal of Dental Research. https://doi.org/10.1177/154405910508400807
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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