The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
A Randomized Controlled Trial of Gravity-Supported, Computer-Enhanced Arm Exercise for Individuals With Severe Hemiparesis
Abstract
Background/Objective. The authors previously developed a passive instrumented arm orthosis (Therapy Wilmington Robotic Exoskeleton [T-WREX]) that enables individuals with hemiparesis to exercise the arm by playing computer games in a gravity-supported environment. The purpose of this study was to compare semiautonomous training with T-WREX and conventional semiautonomous exercises that used a tabletop for gravity support. Methods. Twenty-eight chronic stroke survivors with moderate/severe hemiparesis were randomly assigned to experimental (T-WREX) or control (tabletop exercise) treatment. A blinded rater assessed arm movement before and after twenty-four 1-hour treatment sessions and at 6-month follow-up. Subjects also rated subjective treatment preferences after a single-session crossover treatment. Results. All subjects significantly improved ( P ≤ .05) upper extremity motor control (Fugl-Meyer), active reaching range of motion (ROM), and self-reported quality and amount of arm use (Motor Activity Log). Improvements were sustained at 6 months. The T-WREX group maintained gains on the Fugl-Meyer significantly better than controls at 6 months (improvement of 3.6 ± 3.9 vs 1.5 ± 2.7 points, mean ± SD; P = .04). Subjects also reported a preference for T-WREX training. Conclusion . Gravity-supported arm exercise, using the T-WREX or tabletop support, can improve arm movement ability after chronic severe hemiparesis with brief one-on-one assistance from a therapist (approximately 4 minutes per session). The 3-dimensional weight support, instant visual movement feedback, and simple virtual reality software provided by T-WREX were associated with modest sustained gains at 6-month follow-up when compared with the conventional approach.
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Cites
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Cited by
Harnessing neuroplasticity for clinical applications
Cramer, S. C., Sur, M., Dobkin, B. H., O'Brien, C., Sanger, T. D., Trojanowski, J. Q., Rumsey, J. M., Hicks, R., Cameron, J., Chen, D., et al. (2011) · Brain · doi:10.1093/brain/awr039 · Cited by 1,259
What Is the Evidence for Physical Therapy Poststroke? A Systematic Review and Meta-Analysis
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Review of control strategies for robotic movement training after neurologic injury
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Self-citationVirtual reality for stroke rehabilitation
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Mehrholz, J., Pohl, M., Platz, T., Kugler, J., & Elsner, B. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006876.pub4 · Cited by 678
Metadata
- Authors
- Housman, S. J., Scott, K. M., & Reinkensmeyer, D. J.
- Venue
- Neurorehabilitation and Neural Repair
- Publisher
- SAGE Publications
- Published
- 2009-02-23
- Volume
- 23
- Issue
- 5
- Pages
- 505-514
- ISSN
- 0888-4390 (ISSN-L)
- 1545-9683
- 1552-6844
- OpenAlex
- W2161879265
- Cited by
- 369
- References
- 44
- FWCI
- 28.53
- Type
- journal article
- Language
- en
- Open access
- closed
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