Large Language Models in Spine Surgery: A Promising Technology
Open accessAbstract
Large language models (LLMs) offer potential applications across medical specialties; in spine surgery, opportunities exist to enhance patient care, streamline research, and improve clinical practice. This review explores the current and potential applications of LLMs in spine surgery, assessing their possibilities and limitations across patient education, research, clinical practice, and perioperative assistance.
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Fabricated or hallucinated citations can create a false evidence base that is difficult for a busy clinician or a member of the lay public to verify.
“Fabricated or hallucinated citations can create a false evidence base that is difficult for a busy clinician, much less a member of the lay public, to verify.8”
From Large Language Model Hallucinations in Spine Surgery: A Comparative Analysis of Clinician vs Patient-Level Prompts (2026) · cites this paper as [8]
The Clinical Practice section (page unavailable) reports that GPT-4 generated incorrect citations in half of its responses to neurosurgical questions, and the Discussion warns that hallucinations can produce misleading information. The paper does not say that these citations create a false evidence base or that busy clinicians or members of the public have difficulty verifying them. (LLM, conf=0.85)
Experimental — accuracy not yet measuredLLMs are being explored for utility in spine surgery research and patient education.
“LLMs are being explored for their utility in spine surgery research and patient education, offering to simplify complex medical concepts for patients trying to understand their own conditions, improving healthcare literacy.7,8”
From Large Language Model Hallucinations in Spine Surgery: A Comparative Analysis of Clinician vs Patient-Level Prompts (2026) · cites this paper as [8]
The utility of LLMs is limited by a significant and well-documented flaw: hallucinations.
“The utility of these models is limited by a significant and well-documented flaw: hallucinations.8”
From Large Language Model Hallucinations in Spine Surgery: A Comparative Analysis of Clinician vs Patient-Level Prompts (2026) · cites this paper as [8]
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Cites
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Flagged first, then by citations
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Cited by
Sorted by citations
McLaughlin, N. D., Srinivas, A. N., Lowe, Z. F., Botterbush, K. S., Patel, M. S., & Avila, M. J. (2026) · Neurosurgery Practice · doi:10.1227/neuprac.0000000000000244 · Cited by 1 · see citing works
“8 High rates of citation fabrication have been quanti fi ed in other fi elds, such as a study on systematic reviews in the fi eld of orthopedic surgery conducted by Chelli et al, 12 which found high hallucination rates in ChatGPT.”
- Authors
- Shah, R., & Schwab, J. H.
- Affiliations
- Cedars-Sinai Medical Center (US)
- Corresponding author
- Shah, Romil
- Venue
- HSS Journal®: The Musculoskeletal Journal of Hospital for Special Surgery
- Publisher
- SAGE Publications
- Published
- 2025-05-29
- Volume
- 21
- Issue
- 3
- Pages
- 325-330
- ISSN
- 1556-3316 (ISSN-L)
- 1556-3324
- OpenAlex
- W4410874125
- Cited by
- 5
- References
- 9
- Citations by year
- 2026: 5
- FWCI
- 0.26
- Type
- journal article
- Language
- en
- Open access
- Locations
- HSS Journal® The Musculoskeletal Journal of Hospital for Special Surgery (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (publishedVersion)
- Topics
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Technology and Human Factors in Education and Health
- Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
- Keywords
- large language models, spinal surgery, patient education, clinical practice, medical research, artificial intelligence in healthcare
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