Cited by 101Artificial Intelligence in HealthcareDiabetes Management and ResearchMachine Learning in Healthcare

Toward Big Data Analytics: Review of Predictive Models in Management of Diabetes and Its Complications

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Cichosz, Simon Lebech, Johansen, Mette Dencker, Hejlesen, Ole·2016·Journal of Diabetes Science and Technology

Abstract

Diabetes is one of the top priorities in medical science and health care management, and an abundance of data and information is available on these patients. Whether data stem from statistical models or complex pattern recognition models, they may be fused into predictive models that combine patient information and prognostic outcome results. Such knowledge could be used in clinical decision support, disease surveillance, and public health management to improve patient care. Our aim was to review the literature and give an introduction to predictive models in screening for and the management of prevalent short- and long-term complications in diabetes. Predictive models have been developed for management of diabetes and its complications, and the number of publications on such models has been growing over the past decade. Often multiple logistic or a similar linear regression is used for prediction model development, possibly owing to its transparent functionality. Ultimately, for prediction models to prove useful, they must demonstrate impact, namely, their use must generate better patient outcomes. Although extensive effort has been put in to building these predictive models, there is a remarkable scarcity of impact studies.

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  • A generative model trained on longitudinal data can predict the likelihood of a heart attack or stroke in a diabetic patient, offering clinicians insights that can inform preventative treatment plans.

    “A generative model trained on this data can predict the likelihood of a heart attack or stroke in a diabetic patient, offering clinicians valuable insights that can inform preventative treatment plans (50,51).”

    From Generative artificial intelligence in predictive analysis of diabetes and its complications: a narrative review (2025) · cites this paper as [50]

    The Predictive Models section says models can estimate an individual’s risk and can use time-series data; Heart Disease describes risk scores for patients with diabetes, and the references include stroke-risk models. The paper does not identify a generative model trained on longitudinal data for these outcomes. Heart Disease also cautions that most such models have not been proven valuable in daily care, so their use to inform preventive treatment plans remains unestablished. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • Generative AI has been used to predict the onset of cardiovascular complications in diabetes patients by analyzing longitudinal data including heart rate variability, cholesterol levels, and inflammatory markers.

    “Generative AI has been used to predict the onset of cardiovascular complications in diabetes patients by analyzing longitudinal data, including heart rate variability, cholesterol levels, and inflammatory markers.”

    From Generative artificial intelligence in predictive analysis of diabetes and its complications: a narrative review (2025) · cites this paper as [50]

    The Heart Disease section (page unavailable) reports models that predict heart disease in patients with diabetes and lists cholesterol among their common predictors. The Predictive Models section says model data can include time series, but does not link longitudinal data to those heart-disease models. Neither section supports the claim that generative AI was used or that heart rate variability and inflammatory markers were analyzed. (LLM, conf=0.88)

    Experimental — accuracy not yet measured

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Authors
Cichosz, S. L., Johansen, M. D., & Hejlesen, O.
Affiliations
Aalborg University (DK)
Corresponding author
Cichosz, Simon Lebech
Venue
Journal of Diabetes Science and Technology
Published
2015-10-14
Volume
10
Issue
1
Pages
27-34
ISSN
1932-2968 (ISSN-L)
OpenAlex
W2198326006
Cited by
101
References
125
Citations by year
2026: 5 · 2025: 7 · 2024: 16 · 2023: 8 · 2022: 15 · 2021: 17 · 2020: 4 · 2019: 6 · 2018: 12 · 2017: 8 · 2016: 3
FWCI
0.84
Type
journal article
Language
en
Open access
Locations
  • Journal of Diabetes Science and Technology (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • VBN Forskningsportal (Aalborg Universitet) (submittedVersion, other-oa)
Topics
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
Keywords
diabetes mellitus, prediction model, diabetes complications, clinical decision support, disease surveillance, big data analytics, logistic regression, impact studies, patient outcomes, diabetes management
MeSH terms
Decision Support Techniques, Diabetes Mellitus, Humans, Disease Management, Decision Support Systems, Clinical, Diabetes Complications

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