Meropenem resistant Lactobacillus endocarditis in an immunocompetent patient
Open accessAbstract
Lactobacilli are gram-positive bacteria usually found in the normal flora and are commonly used as probiotic treatments for vaginal candidiasis. Lactobacilli are normally considered non-pathogenic; however, certain risk factors can make a patient susceptible to severe infections. This case describes an immunocompetent 61-year-old female with an automated intracardiac defibrillator who presented with a 10-day history of nausea and vomiting. Furthermore, diagnostic tests, including a transesophageal echocardiography, revealed a large vegetation, and blood cultures were consistently positive for Lactobacillus. The patient was treated with intravenous penicillin and gentamicin, along with removal of the automated intracardiac defibrillator. In patients with significant underlying conditions, physicians should consider Lactobacillus as a causative organism to avoid delays in treatment.
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Lactobacilli can act as opportunistic pathogens causing Lactobacillus bacteremia, endocarditis, liver and dental abscesses, and prosthetic knee infections.
“However, in some cases, lactobacilli can act as opportunistic pathogens causing Lactobacillus bacteremia (LB), endocarditis, liver and dental abscesses, and prosthetic knee infections [2,5,6,7,8].”
From Lactobacillus Bacteremia and Probiotics: A Review (2023) · cites this paper as [8]
The Introduction and Discussion describe Lactobacillus as a cause of bacteremia and endocarditis, particularly in patients with risk factors. Our copy does not report liver or dental abscesses or prosthetic knee infections; its mention of a prosthetic valve concerns endocarditis, not a knee infection. No page numbers are available in the supplied copy. (LLM, conf=0.88)
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Lactobacillus Bacteremia and Probiotics: A Review
Kullar, R., Goldstein, E. J. C., Johnson, S., & McFarland, L. V. (2023) · Microorganisms · doi:10.3390/microorganisms11040896 · Cited by 156 · see citing works
- Authors
- DeMarco, E., DePetrillo, J., & Qadeer, F.
- Affiliations
- Shore Memorial Hospital (US)
- Equum Medical, New York, NY, USA
- Corresponding author
- DeMarco, Elizabeth
- ORCID
- DeMarco, Elizabeth
- Venue
- SAGE Open Medical Case Reports
- Publisher
- SAGE Publications
- Published
- 2023-01
- Volume
- 11
- Pages
- 2050313X231152709-2050313X231152709
- ISSN
- 2050-313X (ISSN-L)
- PMC
- PMC9893053
- OpenAlex
- W4319293639
- Cited by
- 8
- References
- 5
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 1 · 2023: 2
- FWCI
- 1.60
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- SAGE Open Medical Case Reports (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac tumors and thrombi
- Health Sciences › Medicine › Ophthalmology › Ocular Infections and Treatments
- Keywords
- meropenem resistance, infective endocarditis, immunocompetent patient, cardiac vegetation, probiotic bacteria, penicillin therapy, gentamicin, device removal, transesophageal echocardiography
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