The Development and Internal Evaluation of a Predictive Model to Identify for Whom Mindfulness-Based Cognitive Therapy Offers Superior Relapse Prevention for Recurrent Depression Versus Maintenance Antidepressant Medication

Cohen, Zachary D.; DeRubeis, Robert J.; Hayes, Rachel; Watkins, Edward R.; Lewis, Glyn; Byng, Richard; Byford, Sarah; Crane, Catherine; Kuyken, Willem; Dalgleish, Tim; Schweizer, Susanne

doi:10.1177/21677026221076832

The Development and Internal Evaluation of a Predictive Model to Identify for Whom Mindfulness-Based Cognitive Therapy Offers Superior Relapse Prevention for Recurrent Depression Versus Maintenance Antidepressant Medication

Depression is highly recurrent, even following successful pharmacological and/or psychological intervention. We aimed to develop clinical prediction models to inform adults with recurrent depression choosing between antidepressant medication (ADM) maintenance or switching to mindfulness-based cog…