The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury and Central Cord Syndrome: Recommendations on the Timing (≤24 Hours Versus >24 Hours) of Decompressive Surgery
Open accessAbstract
Objective: To develop recommendations on the timing of surgical decompression in patients with traumatic spinal cord injury (SCI) and central cord syndrome. Methods: A systematic review of the literature was conducted to address key relevant questions. A multidisciplinary guideline development group used this information, along with their clinical expertise, to develop recommendations for the timing of surgical decompression in patients with SCI and central cord syndrome. Based on GRADE, a strong recommendation is worded as “we recommend,” whereas a weak recommendation is presented as “we suggest.” Results: Conclusions from the systematic review included (1) isolated studies reported statistically significant and clinically important improvements following early decompression at 6 months and following discharge from inpatient rehabilitation; (2) in one study on acute central cord syndrome without instability, a marginally significant improvement in total motor scores was reported at 6 and 12 months in patients managed with early versus late surgery; and (3) there were no significant differences in length of acute care/rehabilitation stay or in rates of complications between treatment groups. Our recommendations were: “We suggest that early surgery be considered as a treatment option in adult patients with traumatic central cord syndrome” and “We suggest that early surgery be offered as an option for adult acute SCI patients regardless of level.” Quality of evidence for both recommendations was considered low. Conclusions: These guidelines should be implemented into clinical practice to improve outcomes in patients with acute SCI and central cord syndrome by promoting standardization of care, decreasing the heterogeneity of management strategies, and encouraging clinicians to make evidence-informed decisions.
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GRADE guidelines: 3. Rating the quality of evidence
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Fehlings, M. G., Vaccaro, A. R., Wilson, J. R., Singh, A., Cadotte, D. W., Harrop, J. S., Aarabi, B., Shaffrey, C. I., Dvorak, M. F., Fisher, C. G., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0032037 · Cited by 1,242
Self-citationSchneider, R. C., Cherry, G., & Pantek, H. (1954) · Journal of Neurosurgery · doi:10.3171/jns.1954.11.6.0546 · Cited by 593
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Acute Traumatic Spinal Cord Injury
Eli, I., Lerner, D. P., & Ghogawala, Z. (2021) · Neurologic Clinics · doi:10.1016/j.ncl.2021.02.004 · Cited by 285
Cell-based and stem-cell-based treatments for spinal cord injury: evidence from clinical trials
Zipser, C. M., Cragg, J. J., Guest, J. D., Fehlings, M. G., Jutzeler, C. R., Anderson, A. J., & Curt, A. (2022) · The Lancet Neurology · doi:10.1016/s1474-4422(21)00464-6 · Cited by 269
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Metadata
- Authors
- Fehlings, M. G., Tetreault, L. A., Wilson, J. R., Aarabi, B., Anderson, P., Arnold, P. M., Brodke, D. S., Burns, A. S., Chiba, K., Dettori, J. R., Furlan, J. C., Hawryluk, G., Holly, L. T., Howley, S., Jeji, T., Kalsi-Ryan, S., Kotter, M., Kurpad, S., Marino, R. J., Martin, A. R., Massicotte, E., Merli, G., Middleton, J. W., Nakashima, H., Nagoshi, N., Palmieri, K., Singh, A., Skelly, A. C., Tsai, E. C., Vaccaro, A., Yee, A., & Harrop, J. S.
- Venue
- Global Spine Journal
- Publisher
- SAGE Publications
- Published
- 2017-09
- Volume
- 7
- Issue
- 3_suppl
- Pages
- 195S-202S
- ISSN
- 2192-5682 (ISSN-L)
- 2192-5690
- OpenAlex
- W2753195337
- Cited by
- 267
- References
- 17
- FWCI
- 12.42
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury and Central Cord Syndrome: Recommendations on the Timing (≤24 Hours Versus >24 Hours) of Decompressive Surgery. https://app.cochat.ai/papers/10.1177/2192568217706367
- The paper
- Fehlings, M. G., Tetreault, L. A., Wilson, J. R., Aarabi, B., Anderson, P., Arnold, P. M., Brodke, D. S., Burns, A. S., Chiba, K., Dettori, J. R., Furlan, J. C., Hawryluk, G., Holly, L. T., Howley, S., Jeji, T., Kalsi-Ryan, S., Kotter, M., Kurpad, S., Marino, R. J., . . . Harrop, J. S. (2017). A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury and Central Cord Syndrome: Recommendations on the Timing (≤24 Hours Versus >24 Hours) of Decompressive Surgery. Global Spine Journal. https://doi.org/10.1177/2192568217706367
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
