Perivascular support of human hematopoietic stem/progenitor cells
Open accessAbstract
Key Points: Perivascular cells maintain HSPCs ex vivo.
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CD146 expression in MSCs plays a key role in the perivascular niche, skeletogenesis, and hematopoietic support in vivo.
“CD146 expression in MSCs plays a key role in the perivascular niche, skeletogenesis, and hematopoietic support in vivo [26,27,28].”
From Mesenchymal Stem/Stromal Cells: Immunomodulatory and Bone Regeneration Potential after Tumor Excision in Osteosarcoma Patients (2023) · cites this paper as [27]
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References 52 · Cited by 189
- Authors
- Corselli, M., Chin, C. J., Parekh, C., Sahaghian, A., Wang, W., Ge, S., Evseenko, D., Wang, X., Montelatici, E., Lazzari, L., Crooks, G. M., & Péault, B.
- Affiliations
- University of California, Los Angeles (US)
- Children's Hospital Los Angeles (US)
- Molecular Biology Institute,
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2013-04-11
- Volume
- 121
- Issue
- 15
- Pages
- 2891-2901
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- PMC
- PMC3707421
- OpenAlex
- W1987465039
- Cited by
- 189
- References
- 52
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 10 · 2023: 5 · 2022: 8 · 2021: 15 · 2020: 12 · 2019: 11 · 2018: 20 · 2017: 14 · 2016: 28 · 2015: 21 · 2014: 20 · 2013: 15
- FWCI
- 20.09
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Blood (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (K01AR061415)
- Topics
- Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
- Health Sciences › Medicine › Genetics › Mesenchymal stem cell research
- Health Sciences › Medicine › Oncology › Cancer Cells and Metastasis
- Keywords
- hematopoietic stem and progenitor cells, perivascular cells, CD146, hematopoietic niche, mesenchymal stem cells, Notch signaling, cell-cell contact, engraftment, adipose tissue, hematopoiesis
- MeSH terms
- Serrate-Jagged Proteins, Adult, Animals, Blood Vessels, Calcium-Binding Proteins, Cell Communication, Cells, Cultured, Fetal Blood, Hematopoietic Stem Cells, Humans, Immunohistochemistry, Intermediate Filament Proteins, Membrane Proteins, Nerve Tissue Proteins, Blotting, Western, Coculture Techniques, Antigens, CD34, Reverse Transcriptase Polymerase Chain Reaction, Intercellular Signaling Peptides and Proteins, Mice, Receptors, Notch, CD146 Antigen, Chemokine CXCL12, Mesenchymal Stem Cells, Nestin
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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