Cited by 266Acute Lymphoblastic Leukemia researchCell death mechanisms and regulationAcute Myeloid Leukemia Research

The DOI matches its Crossref record; 42 of the 44 references it cites were found in a registry or an index.

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Abstract

Key Points: High levels of the anti-apoptotic factor BCL-2 can be therapeutically exploited by the BH3 mimetic ABT-199 in human T-ALL.

Overview

Integrity signals

Registry

Crossref · 10.1182/blood-2014-05-574566

Cites

42 of 42 references verified0 citation errors · 0 not checkable

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Items 101–200 of 266

Metadata

Authors
Peirs, S., Matthijssens, F., Goossens, S., Van de Walle, I., Ruggero, K., de Bock, C. E., Degryse, S., Canté-Barrett, K., Briot, D., Clappier, E., Lammens, T., De Moerloose, B., Benoit, Y., Poppe, B., Meijerink, J. P., Cools, J., Soulier, J., Rabbitts, T. H., Taghon, T., Speleman, F., & Van Vlierberghe, P.
Affiliations
  • Center for Medical Genetics,
  • Vlaams Instituut voor Biotechnologie (BE)
  • Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Ghent, Belgium;
  • John Radcliffe Hospital (GB)
  • Laboratory for the Molecular Biology of Leukemia, Center for Human Genetics, University of Leuven and Center for the Biology of Disease, Vlaams Instituut voor Biotechnologie, Leuven, Belgium;
  • Erasmus MC (NL)
  • Inserm (FR)
  • Ghent University Hospital (BE)
  • Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium
  • Ghent University (BE)
Venue
Blood
Published
2014-12-11
Volume
124
Issue
25
Pages
3738-3747
ISSN
  • 0006-4971 (ISSN-L)
  • 1528-0020
OpenAlex
W2048591984
Cited by
264
References
44
Citations by year
2026: 12 · 2025: 18 · 2024: 31 · 2023: 29 · 2022: 24 · 2021: 25 · 2020: 22 · 2019: 25 · 2018: 22 · 2017: 18 · 2016: 22 · 2015: 16
FWCI
18.58
Type
journal article
Language
en
Open access
closed
Locations
  • Blood (publishedVersion)
  • PubMed (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
  • EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
  • Ghent University Academic Bibliography (Ghent University) (submittedVersion)
Funders
  • European Hematology Association (TRTH104)
  • Wellcome Trust (099246/Z/12/Z)
  • Agence Nationale de la Recherche (ANR-10-IBHU-0002)
Topics
  • Health Sciences › Medicine › Hematology › Acute Lymphoblastic Leukemia research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cell death mechanisms and regulation
  • Health Sciences › Medicine › Hematology › Acute Myeloid Leukemia Research
Keywords
venetoclax, BCL-2 inhibition, BH3 mimetics, T-cell acute lymphoblastic leukemia, drug synergy, doxorubicin, L-asparaginase, dexamethasone, TLX3, HOXA, TAL1, molecular subtypes, treatment resistance
MeSH terms
Animals, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Cell Survival, Cells, Cultured, Child, Drug Synergism, Humans, Sulfonamides, Tumor Cells, Cultured, Blotting, Western, Gene Expression Regulation, Leukemic, Survival Analysis, Mice, SCID, Mice, Inbred NOD, Bridged Bicyclo Compounds, Heterocyclic, Jurkat Cells, Proto-Oncogene Proteins c-bcl-2, Inhibitory Concentration 50, Reverse Transcriptase Polymerase Chain Reaction, Oligonucleotide Array Sequence Analysis, Gene Expression Profiling, Xenograft Model Antitumor Assays, Cell Line, Tumor, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, HEK293 Cells

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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