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New role for the (pro)renin receptor in T-cell development
Abstract
Key Points: PRR deletion in T cells drastically reduces the number of peripheral and thymic CD3+ T cells. We identify multiple stages of thymocyte development that require PRR expression.
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The (P)RR plays a role in Wnt/β-catenin signaling, vacuolar H+-ATPase integrity, and T-cell development independently of (pro)renin.
“Recently, the (P)RR was reported to play a role in Wnt/β-catenin signaling pathway, vacuolar H+-ATPase integrity, and T-cell development, independently of (pro)renin.26–30”
From (Pro)renin Receptor Inhibition Reprograms Hepatic Lipid Metabolism and Protects Mice From Diet-Induced Obesity and Hepatosteatosis (2018) · cites this paper as [27]
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Research works printed but not linked: 20
- Nguyen, 2002, Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin., J Clin Invest, 109, 1417, 10.1172/JCI0214276 · DOI
- Müller, 2012, Prorenin receptor regulates more than the renin-angiotensin system., Ann Med, 44, S43, 10.3109/07853890.2012.660496 · DOI
- Mahmud, 2014, Cardiac function and architecture are maintained in a model of cardiorestricted overexpression of the prorenin-renin receptor., PLoS ONE, 9, e89929, 10.1371/journal.pone.0089929 · DOI
- Rosendahl, 2014, Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice., Lab Invest, 94, 863, 10.1038/labinvest.2014.83 · DOI
- Batenburg, 2012, (Pro)renin and its receptors: pathophysiological implications., Clin Sci (Lond), 123, 121, 10.1042/CS20120042 · DOI · Paper page
- Burcklé, 2006, Prorenin and its ancient receptor., Hypertension, 48, 549, 10.1161/01.HYP.0000241132.48495.df · DOI
- Oshima, 2011, Prorenin receptor is essential for normal podocyte structure and function., J Am Soc Nephrol, 22, 2203, 10.1681/ASN.2011020202 · DOI · Paper page
- Riediger, 2011, Prorenin receptor is essential for podocyte autophagy and survival., J Am Soc Nephrol, 22, 2193, 10.1681/ASN.2011020200 · DOI · Paper page
- Kinouchi, 2010, The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes., Circ Res, 107, 30, 10.1161/CIRCRESAHA.110.224667 · DOI · Paper page
- Kanda, 2013, Atp6ap2/(pro)renin receptor interacts with Par3 as a cell polarity determinant required for laminar formation during retinal development in mice., J Neurosci, 33, 19341, 10.1523/JNEUROSCI.1362-13.2013 · DOI
- Song, 2013, Deletion of the prorenin receptor from the ureteric bud causes renal hypodysplasia., PLoS ONE, 8, e63835, 10.1371/journal.pone.0063835 · DOI
- Rousselle, 2014, (Pro)renin receptor and V-ATPase: from Drosophila to humans., Clin Sci (Lond), 126, 529, 10.1042/CS20130307 · DOI
- Cruciat, 2010, Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling., Science, 327, 459, 10.1126/science.1179802 · DOI · Paper page
- Buechling, 2010, Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor., Curr Biol, 20, 1263, 10.1016/j.cub.2010.05.028 · DOI
- Hermle, 2010, Regulation of Frizzled-dependent planar polarity signaling by a V-ATPase subunit., Curr Biol, 20, 1269, 10.1016/j.cub.2010.05.057 · DOI
- Xu, 2003, Deletion of beta-catenin impairs T cell development., Nat Immunol, 4, 1177, 10.1038/ni1008 · DOI
- Jeannet, 2008, Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin., Blood, 111, 142, 10.1182/blood-2007-07-102558 · DOI
- Koch, 2008, Simultaneous loss of beta- and gamma-catenin does not perturb hematopoiesis or lymphopoiesis., Blood, 111, 160, 10.1182/blood-2007-07-099754 · DOI
- Narumi, 2015, Functional (pro)renin receptor is expressed in human lymphocytes and monocytes., Am J Physiol Renal Physiol, 308, F487, 10.1152/ajprenal.00206.2014 · DOI
- Gray, 2006, Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells., Blood, 108, 3777, 10.1182/blood-2006-02-004531 · DOI
Cited by
Sorted by citations
The (pro)renin receptor in health and disease
Ichihara, A., & Yatabe, M. S. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0160-5 · Cited by 137
Ren, L., Sun, Y., Lu, H., Ye, D., Han, L., Wang, N., Daugherty, A., Li, F., Wang, M., Su, F., et al. (2018) · Circulation Research · doi:10.1161/circresaha.117.312422 · Cited by 59
Metadata
- Authors
- Geisberger, S., Maschke, U., Gebhardt, M., Kleinewietfeld, M., Manzel, A., Linker, R. A., Chidgey, A., Dechend, R., Nguyen, G., Daumke, O., Muller, D. N., Wright, M. D., & Binger, K. J.
- Affiliations
- Experimental and Clinical Research Center, an institutional cooperation between the Charité Medical Faculty and the Max-Delbruck Center for Molecular Medicine, Berlin, Germany;
- Faculty of Medicine, Dresden University of Technology, Dresden, Germany;
- Department of Neurology, University of Erlangen, Erlangen, Germany;
- Stem Cells and Immune Regeneration Laboratory, Department of Anatomy and Developmental Biology, Monash University, Clayton, Australia;
- INSERM and College de France, Center for Interdisciplinary Research in Biology, Paris, France;
- Max-Delbruck Center for Molecular Medicine, Berlin, Germany;
- Department of Immunology, Monash University, Prahran, Australia
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2015-07-23
- Volume
- 126
- Issue
- 4
- Pages
- 504-507
- ISSN
- 0006-4971
- 1528-0020
- Cited by
- 25
- References
- 0
- Language
- en
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