The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis
Open accessAbstract
Key Points: A BRAF gene fusion and small in-frame BRAF deletions were found in a subset of LCH lesions lacking BRAF-V600E or MAP2K1 mutations. In LCH model systems, responses to MAPK pathway inhibitors depend on the specific genetic alteration that drives ERK activation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Chen, S.-H., Zhang, Y., Van Horn, R. D., Yin, T., Buchanan, S., Yadav, V., Mochalkin, I., Wong, S. S., Yue, Y. G., Huber, L., et al. (2016) · Cancer Discovery · doi:10.1158/2159-8290.cd-15-0896 · Cited by 171
Cited by
Rodriguez-Galindo, C., & Allen, C. E. (2020) · Blood · doi:10.1182/blood.2019000934 · Cited by 361
Self-citationMutually exclusive recurrent KRAS and MAP2K1 mutations in Rosai–Dorfman disease
Garces, S., Medeiros, L. J., Patel, K. P., Li, S., Pina-Oviedo, S., Li, J., Garces, J. C., Khoury, J. D., & Yin, C. C. (2017) · Modern Pathology · doi:10.1038/modpathol.2017.55 · Cited by 299
BRAFV600E-induced senescence drives Langerhans cell histiocytosis pathophysiology
Bigenwald, C., Le Berichel, J., Wilk, C. M., Chakraborty, R., Chen, S. T., Tabachnikova, A., Mancusi, R., Abhyankar, H., Casanova-Acebes, M., Laface, I., et al. (2021) · Nature Medicine · doi:10.1038/s41591-021-01304-x · Cited by 83
Self-citation
Metadata
- Authors
- Chakraborty, R., Burke, T. M., Hampton, O. A., Zinn, D. J., Lim, K. P. H., Abhyankar, H., Scull, B., Kumar, V., Kakkar, N., Wheeler, D. A., Roy, A., Poulikakos, P. I., Merad, M., McClain, K. L., Parsons, D. W., & Allen, C. E.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2016-11-24
- Volume
- 128
- Issue
- 21
- Pages
- 2533-2537
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W2531520225
- Cited by
- 172
- References
- 1
- FWCI
- 10.72
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis. https://app.cochat.ai/papers/10.1182/blood-2016-08-733790
- The paper
- Chakraborty, R., Burke, T. M., Hampton, O. A., Zinn, D. J., Lim, K. P. H., Abhyankar, H., Scull, B., Kumar, V., Kakkar, N., Wheeler, D. A., Roy, A., Poulikakos, P. I., Merad, M., McClain, K. L., Parsons, D. W., & Allen, C. E. (2016). Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis. Blood. https://doi.org/10.1182/blood-2016-08-733790
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
