The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.
Clinical updates in adult immune thrombocytopenia
Open accessAbstract
Immune thrombocytopenia (ITP) occurs in 2 to 4/100 000 adults and results in variable bleeding symptoms and thrombocytopenia. In the last decade, changes in our understanding of the pathophysiology of the disorder have led to the publication of new guidelines for the diagnosis and management of ITP and standards for terminology. Current evidence supports alternatives to splenectomy for second-line management of patients with persistently low platelet counts and bleeding. Long-term follow-up data suggest both efficacy and safety, in particular, for the thrombopoietin receptor agonists and the occurrence of late remissions. Follow-up of patients who have undergone splenectomy for ITP reveals significant potential risks that should be discussed with patients and may influence clinician and patient choice of second-line therapy. Novel therapeutics are in development to address ongoing treatment gaps.
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Cites
Hematological Problems in Pediatric Intensive Care
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The ITP syndrome: pathogenic and clinical diversity
Cines, D. B., Bussel, J. B., Liebman, H. A., & Luning Prak, E. T. (2009) · Blood · doi:10.1182/blood-2009-01-129155 · Cited by 804
T-cell-mediated cytotoxicity toward platelets in chronic idiopathic thrombocytopenic purpura
Olsson, B., Andersson, P.-O., Jernås, M., Jacobsson, S., Carlsson, B., Carlsson, L. M. S., & Wadenvik, H. (2003) · Nature Medicine · doi:10.1038/nm921 · Cited by 669
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Epidemiology of incident immune thrombocytopenia: a nationwide population-based study in France
Moulis, G., Palmaro, A., Montastruc, J.-L., Godeau, B., Lapeyre-Mestre, M., & Sailler, L. (2014) · Blood · doi:10.1182/blood-2014-05-578336 · Cited by 351
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Cited by
Josefsson, E. C., Vainchenker, W., & James, C. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207591 · Cited by 68
Metadata
- Authors
- Lambert, M. P., & Gernsheimer, T. B.
- Venue
- Blood
- Publisher
- American Society of Hematology
- Published
- 2017-05-25
- Volume
- 129
- Issue
- 21
- Pages
- 2829-2835
- ISSN
- 0006-4971 (ISSN-L)
- 1528-0020
- OpenAlex
- W2606110133
- Cited by
- 445
- References
- 57
- FWCI
- 31.12
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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