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STUDIES ON THE MECHANISM OF ERYTHROPOIETIC STIMULATION IN PARABIOTIC RATS DURING HYPOXIA

REISSMANN, KURT R.·1950·Blood

Abstract

Chronic hypoxemia was induced in one partner of a pair of parabiotic rats by exposure to defined gas mixtures with low oxygen content. The other partner of the pair was kept in normal atmosphere throughout the experiment and showed normal values of the oxygen saturation of the blood. The erythropoiesis, estimated by the percentage of nucleated red cells in the bone marrow, showed a statistically significant stimulation in both animals. It is, therefore, concluded that under these experimental conditions, the stimulus is not the partial pressure of oxygen in the bone marrow directly but a humoral factor elicited by the hypoxemia in the one partner and transferred to the other one.

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Metadata

Authors
REISSMANN, K. R.
Venue
Blood
Published
1950-04-01
Volume
5
Issue
4
Pages
372-380
ISSN
  • 0006-4971 (ISSN-L)
  • 1528-0020
OpenAlex
W2413031567
Cited by
278
References
0
FWCI
6.73
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: STUDIES ON THE MECHANISM OF ERYTHROPOIETIC STIMULATION IN PARABIOTIC RATS DURING HYPOXIA. https://app.cochat.ai/papers/10.1182/blood.v5.4.372.372
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REISSMANN, K. R. (1950). STUDIES ON THE MECHANISM OF ERYTHROPOIETIC STIMULATION IN PARABIOTIC RATS DURING HYPOXIA. Blood. https://doi.org/10.1182/blood.v5.4.372.372

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.