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Expression of normal myeloid-associated antigens by acute leukemia cells

Open access
Dinndorf, PA, Andrews, RG, Benjamin, D, Ridgway, D, Wolff, L, Bernstein, ID·1986·Blood

Abstract

Monoclonal antibodies that react with hematopoietic cells and their precursors in a stage and lineage restricted fashion were used in indirect immunofluorescence assays to examine leukemic cells from 105 pediatric age patients. The differentiative states of blasts from 42 patients with acute nonlymphocytic leukemia (ANLL) were defined by these antibodies. When these were compared to their morphologic and histochemical levels of differentiation as defined by the French- American-British (FAB) classification, no direct relationship was found. The reactivity of these antibodies with leukemic cells from 63 patients with acute lymphocytic leukemiA (ALL) was also investigated, and the usefulness of these antibodies in distinguishing leukemias of myeloid from those of lymphoid origin was demonstrated.

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Metadata

Authors
Dinndorf, P., Andrews, R., Benjamin, D., Ridgway, D., Wolff, L., & Bernstein, I.
Venue
Blood
Published
1986-04-01
Volume
67
Issue
4
Pages
1048-1053
ISSN
  • 0006-4971 (ISSN-L)
  • 1528-0020
OpenAlex
W183128447
Cited by
229
References
0
FWCI
3.35
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Expression of normal myeloid-associated antigens by acute leukemia cells. https://app.cochat.ai/papers/10.1182/blood.v67.4.1048.1048
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Dinndorf, P., Andrews, R., Benjamin, D., Ridgway, D., Wolff, L., & Bernstein, I. (1986). Expression of normal myeloid-associated antigens by acute leukemia cells. Blood. https://doi.org/10.1182/blood.v67.4.1048.1048

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