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Cited by 361

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Peripheral blood stem cell versus bone marrow allotransplantation: does the source of hematopoietic stem cells matter?

Körbling, Martin, Anderlini, Paolo·2001·Blood

Abstract

Hematopoietic stem cells from 4 different sources have been or are being used for the reconstitution of lymphohematopoietic function after myeloablative, near-myeloablative, or nonmyeloablative treatment. Bone marrow (BM)–derived stem cells, introduced by E. D. Thomas in 1963,1 are considered the classical stem cell source. Fetal liver stem cell transplantation has been performed on a limited number of patients with aplastic anemia or acute leukemia, but only transient engraftment has been demonstrated.2 Peripheral blood as a stem cell source was introduced in 1981,3 and cord blood was introduced as a source in 1988.4 The various stem cell sources differ in their reconstitutive and immunogenic characteristics, which are based on the proportion of early pluripotent and self-renewing stem cells to lineage-committed late progenitor cells and on the number and characteristics of accompanying “accessory cells” contained in stem cell allografts.

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Crossref · 10.1182/blood.v98.10.2900

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Metadata

Authors
Körbling, M., & Anderlini, P.
Venue
Blood
Published
2001-11-15
Volume
98
Issue
10
Pages
2900-2908
ISSN
  • 0006-4971 (ISSN-L)
  • 1528-0020
OpenAlex
W2024835620
Cited by
361
References
1
FWCI
9.94
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Peripheral blood stem cell versus bone marrow allotransplantation: does the source of hematopoietic stem cells matter? https://app.cochat.ai/papers/10.1182/blood.v98.10.2900
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Körbling, M., & Anderlini, P. (2001). Peripheral blood stem cell versus bone marrow allotransplantation: does the source of hematopoietic stem cells matter? Blood. https://doi.org/10.1182/blood.v98.10.2900

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.