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Cited by 2,064

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Weaning from mechanical ventilation

Boles, J-M., Bion, J., Connors, A., Herridge, M., Marsh, B., Melot, C., Pearl, R., Silverman, H., Stanchina, M., Vieillard-Baron, A., Welte, T.·2007·European Respiratory Journal

Abstract

Weaning covers the entire process of liberating the patient from mechanical support and from the endotracheal tube. Many controversial questions remain concerning the best methods for conducting this process. An International Consensus Conference was held in April 2005 to provide recommendations regarding the management of this process. An 11-member international jury answered five pre-defined questions. 1) What is known about the epidemiology of weaning problems? 2) What is the pathophysiology of weaning failure? 3) What is the usual process of initial weaning from the ventilator? 4) Is there a role for different ventilator modes in more difficult weaning? 5) How should patients with prolonged weaning failure be managed? The main recommendations were as follows. 1) Patients should be categorised into three groups based on the difficulty and duration of the weaning process. 2) Weaning should be considered as early as possible. 3) A spontaneous breathing trial is the major diagnostic test to determine whether patients can be successfully extubated. 4) The initial trial should last 30 min and consist of either T-tube breathing or low levels of pressure support. 5) Pressure support or assist–control ventilation modes should be favoured in patients failing an initial trial/trials. 6) Noninvasive ventilation techniques should be considered in selected patients to shorten the duration of intubation but should not be routinely used as a tool for extubation failure.

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Metadata

Authors
Boles, J.-M., Bion, J., Connors, A., Herridge, M., Marsh, B., Melot, C., Pearl, R., Silverman, H., Stanchina, M., Vieillard-Baron, A., & Welte, T.
Venue
European Respiratory Journal
Published
2007-04-30
Volume
29
Issue
5
Pages
1033-1056
ISSN
  • 0903-1936 (ISSN-L)
  • 1399-3003
OpenAlex
W2142104245
Cited by
2,064
References
7
FWCI
32.03
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Weaning from mechanical ventilation. https://app.cochat.ai/papers/10.1183/09031936.00010206
The paper
Boles, J.-M., Bion, J., Connors, A., Herridge, M., Marsh, B., Melot, C., Pearl, R., Silverman, H., Stanchina, M., Vieillard-Baron, A., & Welte, T. (2007). Weaning from mechanical ventilation. European Respiratory Journal. https://doi.org/10.1183/09031936.00010206

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.