The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Symptom variability in patients with severe COPD: a pan-European cross-sectional study
Open accessAbstract
In between exacerbations, chronic obstructive pulmonary disease (COPD) is usually regarded as a stable condition, but there is increasing recognition of variability in this state. This cross-sectional study assessed patients' perception of symptom variability. Participants were outpatients >45 yrs old with COPD, current or ex-smokers, forced expiratory volume in 1 s (FEV 1) <50% predicted, FEV 1/forced vital capacity <0.7 and no exacerbation leading to therapeutic intervention in the previous 3 months. Patients' perceptions of COPD symptoms and their impact on daily life activities were recorded. Alterations in therapy use in response to COPD worsening were also recorded. COPD symptoms were experienced by 2,258 (92.5%) out of 2,441 patients during the 7 days before interview. Breathlessness was the most common symptom (72.5%). Daily and/or weekly symptom variability was reported by 62.7% of symptomatic patients; the morning was the worst time of day. Factors associated with perception of variability of breathlessness included younger age, symptom severity and recruitment to the study by general practitioners. The perception of variability was significantly different between European countries or regions. Patient-perceived COPD symptoms vary over the day and the week, and impact on daily activities; morning being the worst time of day. The majority of patients appear not to adjust treatment when symptoms worsen.
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Vestbo, J., Hurd, S. S., Agustí, A. G., Jones, P. W., Vogelmeier, C., Anzueto, A., Barnes, P. J., Fabbri, L. M., Martinez, F. J., Nishimura, M., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201204-0596pp · Cited by 15,983
Self-citationRabe, K. F., Hurd, S., Anzueto, A., Barnes, P. J., Buist, S. A., Calverley, P., Fukuchi, Y., Jenkins, C., Rodriguez-Roisin, R., van Weel, C., et al. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200703-456so · Cited by 4,925
Development and first validation of the COPD Assessment Test
Jones, P. W., Harding, G., Berry, P., Wiklund, I., Chen, W.-H., & Kline Leidy, N. (2009) · European Respiratory Journal · doi:10.1183/09031936.00102509 · Cited by 3,198
Outcomes for COPD pharmacological trials: from lung function to biomarkers
Cazzola, M., MacNee, W., Martinez, F. J., Rabe, K. F., Franciosi, L. G., Barnes, P. J., Brusasco, V., Burge, P. S., Calverley, P. M. A., Celli, B. R., et al. (2008) · European Respiratory Journal · doi:10.1183/09031936.00099306 · Cited by 858
Self-citationNg, T.-P. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.1.60 · Cited by 624
The overlap syndrome of asthma and COPD: what are its features and how important is it?
Gibson, P. G., & Simpson, J. L. (2009) · Thorax · doi:10.1136/thx.2008.108027 · Cited by 611
Miravitlles, M. (2004) · Thorax · doi:10.1136/thx.2003.008730 · Cited by 557
Self-citationComparison of normal and asthmatic circadian rhythms in peak expiratory flow rate.
Hetzel, M. R., & Clark, T. J. (1980) · Thorax · doi:10.1136/thx.35.10.732 · Cited by 524
Chronic Obstructive Pulmonary Disease Stage and Health-Related Quality of Life
Ferrer, M., Alonso, J., Morera, J., Marrades, R. M., Khalaf, A., Aguar, M. C., Plaza, V., Prieto, L., & Anto, J. M. (1997) · Annals of Internal Medicine · doi:10.7326/0003-4819-127-12-199712150-00003 · Cited by 431
The Proportional Venn Diagram of Obstructive Lung Disease*
Soriano, J. B., Davis, K. J., Coleman, B., Visick, G., Mannino, D., & Pride, N. B. (2003) · Chest · doi:10.1378/chest.124.2.474 · Cited by 339
Cited by
Tabak, M., VanderValk, P., Hermens, H., Vollenbroek-Hutten, M., & Brusse-Keizer, M. (2014) · International Journal of Chronic Obstructive Pulmonary Disease · doi:10.2147/copd.s60179 · Cited by 196
Rebelo, P., Oliveira, A., Paixão, C., Valente, C., Andrade, L., & Marques, A. (2020) · International Journal of Chronic Obstructive Pulmonary Disease · doi:10.2147/copd.s219480 · Cited by 37
The impact of unpredictability on dyspnea perception, anxiety and interoceptive error processing
Tan, Y., Van den Bergh, O., Qiu, J., & von Leupoldt, A. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00535 · Cited by 22
Metadata
- Authors
- Kessler, R., Partridge, M. R., Miravitlles, M., Cazzola, M., Vogelmeier, C., Leynaud, D., & Ostinelli, J.
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2010-11-29
- Volume
- 37
- Issue
- 2
- Pages
- 264-272
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2125373114
- Cited by
- 388
- References
- 27
- FWCI
- 11.31
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Kessler, R., Partridge, M. R., Miravitlles, M., Cazzola, M., Vogelmeier, C., Leynaud, D., & Ostinelli, J. (2011). Symptom variability in patients with severe COPD: a pan-European cross-sectional study. European Respiratory Journal. https://doi.org/10.1183/09031936.00051110
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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