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ERS/ATS statement on interventional pulmonology: Chairmen: C.T. Bolliger, P.N. Mathur
Open accessAbstract
We investigated whether the time between synthesis and injection and the resulting decrease in specific activity affects the normal-organ and tumor uptake of the PSMA ligand 18F-rhPSMA-7.3 in patients with prostate cancer. Methods: The biodistribution of 18F-rhPSMA-7.3 on PET/CT scans obtained with a high specific activity (median, 178.9 MBq/µg; n = 42) and a low specific activity (median, 19.3 MBq/µg; n = 42) was compared. Results: Tracer uptake by the parotid gland, submandibular gland, and spleen was moderately but significantly lower in the low-specific-activity group than in the high-specific-activity group (median SUVmean, 16.7 vs. 19.2; 18.1 vs. 22.3; and 7.8 vs. 9.6, respectively). No other statistically significant differences were found for normal organs or tumor lesions. Conclusion: A 10-fold decrease in specific activity has only minor effects on the biodistribution of 18F-rhPSMA-7.3. These findings suggest that 18F-labeled PSMA ligands can be centrally produced and shipped to PET clinics in a similar way to 18F-FDG.
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Through the looking glass: Differential noradenergic modulation of prefrontal cortical function
Arnsten, A. F. T. (2000) · Neural Plasticity · doi:10.1155/np.2000.133 · Cited by 229
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Yasufuku, K., Chiyo, M., Sekine, Y., Chhajed, P. N., Shibuya, K., Iizasa, T., & Fujisawa, T. (2004) · Chest · doi:10.1378/chest.126.1.122 · Cited by 710
Metadata
- Authors
- Beamis, J. F., Becker, H. D., Cavaliere, S., Colt, H., Diaz-Jimenez, J. P., Dumon, J. F., Edell, E., Kovitz, K. L., Macha, H. N., Mehta, A. C., Marel, M., Noppen, M., Strausz, J., & Sutedja, T. G.
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2002-02
- Volume
- 19
- Issue
- 2
- Pages
- 356-373
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2107972181
- Cited by
- 546
- References
- 1
- FWCI
- 7.75
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Beamis, J. F., Becker, H. D., Cavaliere, S., Colt, H., Diaz-Jimenez, J. P., Dumon, J. F., Edell, E., Kovitz, K. L., Macha, H. N., Mehta, A. C., Marel, M., Noppen, M., Strausz, J., & Sutedja, T. G. (2002). ERS/ATS statement on interventional pulmonology: Chairmen: C.T. Bolliger, P.N. Mathur. European Respiratory Journal. https://doi.org/10.1183/09031936.02.00204602
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
