Mortality in severe sleep apnoea/hypopnoea syndrome patients: impact of treatment
Open accessAbstract
The aim of this study was to determine mortality in patients with sleep apnoea/hypopnoea syndrome (SAHS) according to the treatments employed and comorbidity. An historical cohort of patients with SAHS diagnosed at a university hospital between 1982 and 1992 and followed until 1996 was studied. From a total of 475 SAHS patients, 444 (94%), with a mean±sd apnoea/hypopnoea index at diagnosis of 55±27, were located and included in the study. SAHS treatments employed were: surgery (88), weight loss (134), continuous positive airway pressure (124) and 98 patients were not treated. By the end of follow-up, 49 patients had died. According to Cox regression analysis, mortality in treated patients was lower than in those not treated, but higher in those with a history of severe chronic obstructive pulmonary disease. Mortality in nontreated patients compared with that of the general population, adjusted for age and sex, showed excessive mortality, which decreased in treated patients. Stratification by age showed a greater mortality rate ratio in patients <50 yrs. These findings were maintained when mortality from cardiovascular causes was compared. In conclusion, a rise in mortality was found in nontreated sleep apnoea/hypopnoea syndrome patients compared with the general population, whereas mortality in those treated for sleep apnoea/hypopnoea syndrome did not differ significantly from that of the general population.
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References 34 · Cited by 246
Research works printed but not linked: 3
- [18]18. Montserrat JM, Amilibia J, Barbe F, Capote F, Duran J, Mangado NG. Tratamiento del sı ´ndrome de apnea-hipopnea del suen ˜o. Arch Bronconeumol 1998; 34: 204-206.
- [25]25. Podszus T, Greenberg H, Charf SM. Influence of sleep state and sleep-disordered breathing on cardiovascular function. In: Saunders NA, Sullivan CE, eds. Sleep and Breathing. New York, Marcel Dekker Inc., 1994; pp. 257-310.
- [26]26. Alarcon A, Leon C, Maimo A, Barbe F, Agusti AG, Rodriguez-Roisin R. Compliance with nasal conti- nuous positive airway pressure (CPAP) treatment in sleep apnoea-hypopnoea syndrome. Arch Bronconeu- mol 1995; 31: 56-61.
- Authors
- Marti, S., Sampol, G., Muñoz, X., Torres, F., Roca, A., Lloberes, P., Sagalés, T., Quesada, P., & Morell, F.
- Affiliations
- Universitat Autònoma de Barcelona (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Venue
- European Respiratory Journal
- Publisher
- European Respiratory Society (ERS)
- Published
- 2002-12
- Volume
- 20
- Issue
- 6
- Pages
- 1511-1518
- ISSN
- 0903-1936 (ISSN-L)
- 1399-3003
- OpenAlex
- W2113765726
- Cited by
- 246
- References
- 34
- Citations by year
- 2025: 4 · 2024: 4 · 2023: 6 · 2022: 6 · 2021: 4 · 2020: 11 · 2019: 8 · 2018: 5 · 2017: 8 · 2016: 7 · 2015: 6 · 2014: 8 · 2013: 13 · 2012: 18
- FWCI
- 4.40
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Respiratory Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
- Keywords
- sleep apnea-hypopnea syndrome, mortality, treatment outcomes, continuous positive airway pressure, weight loss, chronic obstructive pulmonary disease, cardiovascular mortality, comorbidities, apnea-hypopnea index
- MeSH terms
- Diet, Reducing, Female, Follow-Up Studies, Humans, Male, Middle Aged, Positive-Pressure Respiration, Risk Factors, Sleep Apnea Syndromes, Time Factors, Comorbidity, Proportional Hazards Models
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