Cited by 366Chronic Obstructive Pulmonary Disease (COPD) ResearchAsthma and respiratory diseasesCystic Fibrosis Research Advances

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Risk factors for rehospitalisation in COPD: role of health status, anxiety and depression

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Gudmundsson, G., Gislason, T., Janson, C., Lindberg, E., Hallin, R., Ulrik, C. S., Brøndum, E., Nieminen, M. M., Aine, T., Bakke, P.·2005·European Respiratory Journal

DOI 10.1183/09031936.05.00078504

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Abstract

The aim of the present study was to analyse the risk of rehospitalisation in patients with chronic obstructive pulmonary disease and associated risk factors. This prospective study included 416 patients from a university hospital in each of the five Nordic countries. Data included demographic information, spirometry, comorbidity and 12 month follow-up for 406 patients. The hospital anxiety and depression scale and St. George's Respiratory Questionnaire (SGRQ) were applied to all patients. The number of patients that had a re-admission within 12 months was 246 (60.6%). Patients that had a re-admission had lower lung function and health status. A low forced expiratory volume in one second (FEV 1) and health status were independent predictors for re-admission. Hazard ratio (HR; 95% CI) was 0.82 (0.74–0.90) per 10% increase of the predicted FEV 1 and 1.06 (1.02–1.10) per 4 units increase in total SGRQ score. The risk of rehospitalisation was also increased in subjects with anxiety (HR 1.76 (1.16–2.68)) and in subjects with low health status (total SGRQ score >60 units). When comparing the different subscales in the SGRQ, the closest relation between the risk of rehospitalisation was seen with the activity scale (HR 1.07 (1.03–1.11) per 4 unit increase). In patients with low health status, anxiety is an important risk factor for rehospitalisation. This may be important for patient treatment and warrants further studies.

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Authors: Gudmundsson, G., Gislason, T., Janson, C., Lindberg, E., Hallin, R., Ulrik, C. S., Brøndum, E., Nieminen, M. M., Aine, T., & Bakke, P.
Affiliations: National University Hospital of Iceland (IS)
Uppsala University (SE)
Amager Hospital (DK)
University of Copenhagen (DK)
Tampere University Hospital (FI)
Haukeland University Hospital (NO)
ORCID: Janson, C.
Lindberg, E.
Ulrik, C. S.
Brøndum, E.
Venue: European Respiratory Journal
Publisher: European Respiratory Society (ERS)
Published: 2005-09
Volume: 26
Issue: 3
Pages: 414-419
ISSN: 0903-1936 (ISSN-L)
1399-3003
DOI: 10.1183/09031936.05.00078504
OpenAlex: W2123606343
Cited by: 366
References: 29
Citations by year: 2026: 6 · 2025: 8 · 2024: 15 · 2023: 17 · 2022: 15 · 2021: 7 · 2020: 13 · 2019: 12 · 2018: 16 · 2017: 24 · 2016: 18 · 2015: 27 · 2014: 22 · 2013: 23 · 2012: 19
FWCI: 14.70
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: European Respiratory Journal (publishedVersion)
PubMed (publishedVersion)
Hirsla (Landspítali University Hospital) (submittedVersion)
Funders: Riksförbundet HjärtLung
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cystic Fibrosis Research Advances
Keywords: chronic obstructive pulmonary disease, hospital readmission, risk factors, anxiety, depression, health status, St George's Respiratory Questionnaire, lung function, FEV1, comorbidities, activity limitation
MeSH terms: Aged, Aged, 80 and over, Anxiety, Depression, Female, Follow-Up Studies, Health Status, Health Surveys, Humans, Male, Middle Aged, Patient Readmission, Prospective Studies, Risk Factors, Pulmonary Disease, Chronic Obstructive

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Risk factors for rehospitalisation in COPD: role of health status, anxiety and depression

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