Cited by 1,668Respiratory Support and MechanismsObstructive Sleep Apnea ResearchNeonatal Respiratory Health Research

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Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure

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Rochwerg, Bram, Brochard, Laurent, Elliott, Mark W., Hess, Dean, Hill, Nicholas S., Nava, Stefano, Navalesi, Paolo, Antonelli, Massimo, Brozek, Jan, Conti, Giorgio, Ferrer, Miquel, Guntupalli, Kalpalatha, Jaber, Samir, Keenan, Sean, Mancebo, Jordi, Mehta, Sangeeta, Raoof, Suhail·2017·European Respiratory Journal

DOI 10.1183/13993003.02426-2016

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Abstract

Noninvasive mechanical ventilation (NIV) is widely used in the acute care setting for acute respiratory failure (ARF) across a variety of aetiologies. This document provides European Respiratory Society/American Thoracic Society recommendations for the clinical application of NIV based on the most current literature. The guideline committee was composed of clinicians, methodologists and experts in the field of NIV. The committee developed recommendations based on the GRADE (Grading, Recommendation, Assessment, Development and Evaluation) methodology for each actionable question. The GRADE Evidence to Decision framework in the guideline development tool was used to generate recommendations. A number of topics were addressed using technical summaries without recommendations and these are discussed in the supplementary material. This guideline committee developed recommendations for 11 actionable questions in a PICO (population–intervention–comparison–outcome) format, all addressing the use of NIV for various aetiologies of ARF. The specific conditions where recommendations were made include exacerbation of chronic obstructive pulmonary disease, cardiogenic pulmonary oedema, de novo hypoxaemic respiratory failure, immunocompromised patients, chest trauma, palliation, post-operative care, weaning and post-extubation. This document summarises the current state of knowledge regarding the role of NIV in ARF. Evidence-based recommendations provide guidance to relevant stakeholders.

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Authors: Rochwerg, B., Brochard, L., Elliott, M. W., Hess, D., Hill, N. S., Nava, S., Navalesi, P., Antonelli, M., Brozek, J., Conti, G., Ferrer, M., Guntupalli, K., Jaber, S., Keenan, S., Mancebo, J., Mehta, S., & Raoof, S.
Affiliations: McMaster University (CA)
St. Michael's Hospital (CA)
St James's University Hospital (GB)
Harvard University (US)
Tufts Medical Center (US)
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola (IT)
Magna Graecia University (IT)
Agostino Gemelli University Polyclinic (IT)
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
Baylor College of Medicine (US)
Inserm (FR)
Royal Columbian Hospital (CA)
Hospital de Sant Pau (ES)
Mount Sinai Hospital (CA)
Hofstra University (US)
ORCID: Rochwerg, Bram
Brochard, Laurent
Elliott, Mark W.
Hill, Nicholas S.
Navalesi, Paolo
Antonelli, Massimo
Conti, Giorgio
Ferrer, Miquel
Jaber, Samir
Keenan, Sean
Mancebo, Jordi
Mehta, Sangeeta
Venue: European Respiratory Journal
Publisher: European Respiratory Society (ERS)
Published: 2017-08
Volume: 50
Issue: 2
Pages: 1602426
ISSN: 0903-1936 (ISSN-L)
1399-3003
DOI: 10.1183/13993003.02426-2016
OpenAlex: W2753000083
Cited by: 1,668
References: 151
Citations by year: 2026: 164 · 2025: 174 · 2024: 151 · 2023: 248 · 2022: 211 · 2021: 235 · 2020: 252 · 2019: 137 · 2018: 83 · 2017: 6
FWCI: 107.26
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: European Respiratory Journal (publishedVersion)
PubMed (publishedVersion)
Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
HAL (submittedVersion, other-oa)
Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
Padua Research Archive (University of Padova) (submittedVersion)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Neonatal Respiratory Health Research
Keywords: non-invasive ventilation, acute respiratory failure, COPD exacerbations, cardiogenic pulmonary edema, hypoxemic respiratory failure, immunocompromised patients, thoracic trauma, palliative care, postoperative care, weaning, post-extubation care
MeSH terms: Acute Disease, Critical Care, Diagnosis, Differential, Humans, Respiratory Insufficiency, Practice Guidelines as Topic, Noninvasive Ventilation

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