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A review on SNP and other types of molecular markers and their use in animal genetics

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Vignal, Alain, Milan, Denis, SanCristobal, Magali, Eggen, André·2002·Genetics Selection Evolution

Abstract

During the last ten years, the use of molecular markers, revealing polymorphism at the DNA level, has been playing an increasing part in animal genetics studies. Amongst others, the microsatellite DNA marker has been the most widely used, due to its easy use by simple PCR, followed by a denaturing gel electrophoresis for allele size determination, and to the high degree of information provided by its large number of alleles per locus. Despite this, a new marker type, named SNP, for Single Nucleotide Polymorphism, is now on the scene and has gained high popularity, even though it is only a bi-allelic type of marker. In this review, we will discuss the reasons for this apparent step backwards, and the pertinence of the use of SNPs in animal genetics, in comparison with other marker types.

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Metadata

Authors
Vignal, A., Milan, D., SanCristobal, M., & Eggen, A.
Venue
Genetics Selection Evolution
Published
2002-05-15
Volume
34
Issue
3
Pages
275-305
ISSN
  • 0999-193X (ISSN-L)
  • 1297-9686
OpenAlex
W2103850807
Cited by
1,040
References
3
FWCI
9.34
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: A review on SNP and other types of molecular markers and their use in animal genetics. https://app.cochat.ai/papers/10.1186/1297-9686-34-3-275
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Vignal, A., Milan, D., SanCristobal, M., & Eggen, A. (2002). A review on SNP and other types of molecular markers and their use in animal genetics. Genetics Selection Evolution. https://doi.org/10.1186/1297-9686-34-3-275

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