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CellProfiler Analyst: data exploration and analysis software for complex image-based screens
Open accessAbstract
Background: Image-based screens can produce hundreds of measured features for each of hundreds of millions of individual cells in a single experiment. Results: Here, we describe CellProfiler Analyst, open-source software for the interactive exploration and analysis of multidimensional data, particularly data from high-throughput, image-based experiments. Conclusion: The system enables interactive data exploration for image-based screens and automated scoring of complex phenotypes that require combinations of multiple measured features per cell.
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Cites
Retinoid-induced bone thinning is caused by subperiosteal osteoclast activity in adult rodents
Kneissel, M., Studer, A., Cortesi, R., & Šuša, M. (2005) · Bone · doi:10.1016/j.bone.2004.11.006 · Cited by 75
Cited by
Data-analysis strategies for image-based cell profiling
Caicedo, J. C., Cooper, S., Heigwer, F., Warchal, S., Qiu, P., Molnar, C., Vasilevich, A. S., Barry, J. D., Bansal, H. S., Kraus, O., et al. (2017) · Nature Methods · doi:10.1038/nmeth.4397 · Cited by 739
Self-citationhistoCAT: analysis of cell phenotypes and interactions in multiplex image cytometry data
Schapiro, D., Jackson, H. W., Raghuraman, S., Fischer, J. R., Zanotelli, V. R. T., Schulz, D., Giesen, C., Catena, R., Varga, Z., & Bodenmiller, B. (2017) · Nature Methods · doi:10.1038/nmeth.4391 · Cited by 659
Imaging cytosolic NADH-NAD(+) redox state with a genetically encoded fluorescent biosensor
Hung, Y. P., Albeck, J. G., Tantama, M., & Yellen, G. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.08.012 · Cited by 509
Basic Image Analysis and Manipulation in ImageJ
Hartig, S. M. (2013) · Current Protocols in Molecular Biology · doi:10.1002/0471142727.mb1415s102 · Cited by 386
Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues
De Cecco, M., Criscione, S. W., Peterson, A. L., Neretti, N., Sedivy, J. M., & Kreiling, J. A. (2013) · Aging · doi:10.18632/aging.100621 · Cited by 365
Metadata
- Authors
- Jones, T. R., Kang, I. H., Wheeler, D. B., Lindquist, R. A., Papallo, A., Sabatini, D. M., Golland, P., & Carpenter, A. E.
- Venue
- BMC Bioinformatics
- Published
- 2008-11-15
- Volume
- 9
- Issue
- 1
- Pages
- 482-482
- ISSN
- 1471-2105 (ISSN-L)
- OpenAlex
- W2139442812
- Cited by
- 541
- References
- 1
- FWCI
- 7.09
- Type
- journal article
- Language
- en
- Open access
- gold
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- Jones, T. R., Kang, I. H., Wheeler, D. B., Lindquist, R. A., Papallo, A., Sabatini, D. M., Golland, P., & Carpenter, A. E. (2008). CellProfiler Analyst: data exploration and analysis software for complex image-based screens. BMC Bioinformatics. https://doi.org/10.1186/1471-2105-9-482
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