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Better prediction of functional effects for sequence variants

Hecht, Maximilian, Bromberg, Yana, Rost, Burkhard·2015·BMC Genomics
DOI 10.1186/1471-2164-16-s8-s1PMC PMC4480835
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  • SNAP2 identified somatic mutations with high likelihood of functional impairment, accounting for 25-52% of total 235 missense mutations depending on evaluation stringency.

    “We first used the SNAP2 tool to assess the potential impact of the missense mutations32, through which we identified a number of somatic mutations with high likelihood of functional impairment, accounting for 25 – 52% of total 235 missense mutations, depending on the evaluation stringency (Extended Data Table 2).”

    From Structural organization of the retriever–CCC endosomal recycling complex (2024) · cites this paper as [32]

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Metadata

Authors
Hecht, M., Bromberg, Y., & Rost, B.
Venue
BMC Genomics
Publisher
Springer Science and Business Media LLC
Published
2015-06-18
Volume
16
Issue
S8
ISSN
1471-2164
DOI
10.1186/1471-2164-16-s8-s1
PMC
PMC4480835
Cited by
569
References
5
Language
en

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