The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Prevalence of frailty and its ability to predict in hospital delirium, falls, and 6-month mortality in hospitalized older patients
Open accessAbstract
BACKGROUND: The prevalence and significance of frailty are seldom studied in hospitalized patients. Aim of this study is to evaluate the prevalence of frailty and to determine the extent that frailty predicts delirium, falls and mortality in hospitalized older patients. METHODS: In a prospective study of 220 older patients, frailty was determined using the Cardiovascular Health Study (CHS) and the Study of Osteoporotic Fracture (SOF) frailty index. Patients were classified as nonfrail, prefrail, and frail, according to the specific criteria. Covariates included clinical and laboratory parameters. Outcome variables included in hospital delirium and falls, and 6-month mortality. RESULTS: The CHS frailty index was available in all 220 patients, of which 1.5% were classified as being nonfrail, 58.5% as prefrail, and 40% as frail. The SOF frailty index was available in 204 patients, of which 16% were classified as being nonfrail, 51.5% as prefrail, and 32.5% as frail. Frailty, as identified by the CHS and SOF indexes, was a significant risk factor for 6-month mortality. However, after adjustment for multiple risk factors, frailty remained a strong independent risk factor only for the model with the CHS index (OR 4.7, 95% CI 1.7-12.8). Frailty (identified by CHS and SOF indexes) was not found to be a risk factor for delirium or falls. CONCLUSIONS: Frailty, as measured by the CHS index, is an independent risk factor for 6-month mortality. The CHS and the SOF indexes have limited value as risk assessment tools for specific geriatric syndromes (e.g., falls and delirium) in hospitalized older patients.
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Frailty in Older Adults: Evidence for a Phenotype
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Clarifying Confusion: The Confusion Assessment Method: A New Method for Detection of Delirium
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Frailty as a predictor of surgical outcomes in older patients
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Interventions for preventing delirium in hospitalised non-ICU patients
Siddiqi, N., Harrison, J. K., Clegg, A., Teale, E. A., Young, J., Taylor, J., & Simpkins, S. A. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005563.pub3 · Cited by 619
Predisposing and Precipitating Factors Associated With Delirium: A Systematic Review
Ormseth, C. H., LaHue, S. C., Oldham, M. A., Josephson, S. A., Whitaker, E., & Douglas, V. C. (2023) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.49950 · Cited by 316
What do we know about frailty in the acute care setting? A scoping review
Theou, O., Squires, E., Mallery, K., Lee, J. S., Fay, S., Goldstein, J., Armstrong, J. J., & Rockwood, K. (2018) · BMC Geriatrics · doi:10.1186/s12877-018-0823-2 · Cited by 312
Impact of COVID-19 in the Mental Health in Elderly: Psychological and Biological Updates
Grolli, R. E., Mingoti, M. E. D., Bertollo, A. G., Luzardo, A. R., Quevedo, J., Réus, G. Z., & Ignácio, Z. M. (2021) · Molecular Neurobiology · doi:10.1007/s12035-020-02249-x · Cited by 258
Gasteiger, N., Loveys, K., Law, M., & Broadbent, E. (2021) · Clinical Interventions in Aging · doi:10.2147/cia.s282709 · Cited by 153
Metadata
- Authors
- Joosten, E., Demuynck, M., Detroyer, E., & Milisen, K.
- Venue
- BMC Geriatrics
- Published
- 2014-01-06
- Volume
- 14
- Issue
- 1
- Pages
- 1-1
- ISSN
- 1471-2318 (ISSN-L)
- OpenAlex
- W2053142053
- Cited by
- 400
- References
- 43
- FWCI
- 18.13
- Type
- journal article
- Language
- en
- Open access
- gold
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