Asthma caused by occupational exposures is common - a systematic analysis of estimates of the population-attributable fraction
Open accessAbstract
BACKGROUND: The aim of this paper is to highlight emerging data on occupational attributable risk in asthma. Despite well documented outbreaks of disease and the recognition of numerous specific causal agents, occupational exposures previously had been relegated a fairly minor role relative to other causes of adult onset asthma. In recent years there has been a growing recognition of the potential importance of asthma induced by work-related exposures METHODS: We searched Pub Med from June 1999 through December 2007. We identified six longitudinal general population-based studies; three case-control studies and eight cross-sectional analyses from seven general population-based samples. For an integrated analysis we added ten estimates prior to 1999 included in a previous review. RESULTS: The longitudinal studies indicate that 16.3% of all adult-onset asthma is caused by occupational exposures. In an overall synthesis of all included studies the overall median PAR value was 17.6%. CONCLUSION: Clinicians should consider the occupational history when evaluating patients in working age who have asthma. At a societal level, these findings underscore the need for further preventive action to reduce the occupational exposures to asthma-causing agents.
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This figure is largely derived from populations in high income countries.
“Of note, this figure can vary widely (from 4 to 58%) (144) and is largely derived from populations in high income countries (144–146).”
From Epidemiology of Asthma in Children and Adults (2019) · cites this paper as [146]
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References 56 · Cited by 285
Research works printed but not linked: 1
- Rothman KJ Geenland S Modern epidemiology 1998 2 Lippincott-Raven, Philadelphia, USA
- Authors
- Torén, K., & Blanc, P. D.
- Affiliations
- Sahlgrenska University Hospital (SE)
- University of California, San Francisco (US)
- Corresponding author
- Torén, Kjell
- Venue
- BMC Pulmonary Medicine
- Published
- 2009-01-29
- Volume
- 9
- Issue
- 1
- Pages
- 7-7
- ISSN
- 1471-2466 (ISSN-L)
- PMC
- PMC2642762
- OpenAlex
- W1987625335
- Cited by
- 285
- References
- 56
- Citations by year
- 2026: 13 · 2025: 5 · 2024: 9 · 2023: 3 · 2022: 6 · 2021: 5 · 2020: 12 · 2019: 23 · 2018: 22 · 2017: 19 · 2016: 21 · 2015: 27 · 2014: 22 · 2013: 30 · 2012: 30
- FWCI
- 22.52
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Pulmonary Medicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Vetenskapsrådet
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Social Sciences › Health › Occupational Health and Global Justice
- Keywords
- occupational asthma, occupational exposure, population attributable fraction, adult-onset asthma, occupational risk factors, occupational history, asthma prevention
- MeSH terms
- Asthma, Cross-Sectional Studies, Health Maintenance Organizations, Humans, Longitudinal Studies, Risk Factors, Global Health, Incidence, Case-Control Studies, Occupational Exposure
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