The DOI matches its Crossref record.
Estimating the burden of malaria in pregnancy: a case study from rural Madhya Pradesh, India
Open accessAbstract
BACKGROUND: Malaria in pregnancy (MiP) is inadequately researched in India, and the burden is probably much higher than current estimates suggest. This paper models the burden of MiP and associated foetal losses and maternal deaths, in rural Madhya Pradesh, India. METHODS: Number of pregnancies per year was estimated from the number of births and an estimate of pregnancies that end in foetal loss. The prevalence of MiP, risk of foetal loss attributable to MiP and case fatality rate of MiP were obtained from the literature. The estimated total number of pregnancies was multiplied by the appropriate parameter to estimate the number of MiP cases, and foetal loss and maternal deaths attributable to MiP per year. A Monte Carlo simulation sensitivity analysis was done to assess plausibility of various estimates obtained from the literature. The burden of MiP in tribal women was explored by incorporating the variable prevalence of malaria in tribal and non-tribal populations and in forested and non-forested regions within Madhya Pradesh. RESULTS: Estimates of MiP cases in rural Madhya Pradesh based on the model parameter values found in the literature ranged from 183,000-1.5 million per year, with 73,000-629,000 lost foetuses and 1,500-12,600 maternal deaths attributable to MiP. The Monte Carlo simulation gave a more plausible estimate of 220,000 MiP cases per year (inter-quartile range (IQR): 136,000-305,000), 95,800 lost foetuses (IQR: 56,800-147,600) and 1,000 maternal deaths (IQR: 650-1,600). Tribal women living in forested areas bore 30% of the burden of MiP in Madhya Pradesh, while constituting 18% of the population. CONCLUSION: Although the estimates are uncertain, they suggest MiP is a significant public health problem in rural Madhya Pradesh, affecting many thousands of women and that reducing the MiP burden should be a priority.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Malaria infection during pregnancy increases the risk of infant's death and perinatal mortality by causing low birth weight.
“It also increases the risk of infant’s death and perinatal mortality, by causing LBW.39,53,55”
From Malaria in pregnancy. (2013) · cites this paper as [55]
The Discussion (page unavailable) reports that malaria in pregnancy may increase the risk of low birth weight and estimates a burden of stillbirths. It does not establish that low birth weight causes the fetal deaths, nor does it report infant mortality through that pathway; it cautions that its findings show correlation, not necessarily causation. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 25
- Duffy P, Fried M: Malaria in Pregnancy: Deadly Parasite, Susceptible Host. 2001, London; New York: Taylor and Francis · DOI
- National Vector Borne Disease Control Programme: Joint Monitoring Mission Report. 2007, National Vector Bourne Disease Control Programme: New Delhi, India
- Bhattacharya , Sharma C, Dhiman RC, Mitra AP: Climate change and malaria in India. Current Science. 2006, 90: 369-375.
- Hay S, Guerra C, Tatem A, Noor A, Snow R: The global distribution and population at risk of malaria: past, present and future. Lancet Infect Dis. 2004, 4: 327-336. 10.1016/S1473-3099(04)01043-6. · DOI
- Korenromp E: Malaria Incidence Estimates at Country Level for the Year 2004. 2005, World Health Organization, Roll Back Malaria
- Matta S, Khokhar A, Sachdev TR: Assessment of knowledge about malaria among patients reported with fever: a hospital based study. Journal of Vector Borne Disease. 2004, 41: 27-31.
- Singh N, Mishra AK, Shukla MM, Chand SK: Forest Malaria in Chhindwara, Madhya Pradesh, Central India: a case study in a tribal community. American Journal of Tropical Medical Hygiene. 2003, 68 (5): 602-607. · DOI
- Guilmoto CZ, Rajan SI: District level estimates of Fertility from India's 2001 Census. Economic and Political Weekly. 2002, 665-672.
- Government of India: Census of India. 2001
- Stanton C, Lawn J, Rahman H, Wilczynska-Ketende K, Hill K: Stillbirth rates: delivering estimates in 190 countries. The Lancet. 2006, 367: 1487-1494. 10.1016/S0140-6736(06)68586-3. · DOI
- Curtis C: Meeting Health Care Needs of Women Experiencing Complications of Miscarriage and Unsafe Abortion: USAID's Postabortion Care Program. Journal of Midwifery and Women's Health. 2007, 52: 368-375. 10.1016/j.jmwh.2007.03.005. · DOI · Paper page
- Das Gupta RK: Epidemiological Situation Report of Madhya Pradesh up to December 2006. Edited by: Chandramohan D, Diamond-Smith N. 2007
- Singh N, Saxena A, Awadhia SB, Shrivastavar R, Singh MP: Evaluation of a rapid diagnostic test for assessing the burden of malaria at delivery in India. Am J Trop Med Hyg. 2005, 73 (5): 855-858. · DOI
- Singh N, Shukla MM, Sharma VP: Epidemiology of malaria in pregnancy in central India. Bull World Health Organ. 1999, 77 (7): 567-572.
- Singh N, Saxena A, Chand SK, Valecha N, Sharma VP: Studies on malaria during pregnancy in a tribal area of central India (MP). The Southeastern Journal of Tropical Medicine and Public Health. 1998, 29:
- Singh N, Mehra RK, Srivastava N: Malaria during pregnancy and infancy, in an area of intense malaria transmission in central India. Annals of Tropical Medicine and Parasitology. 2001, 95 (1): 19-29. 10.1080/00034980020035889. · DOI
- Konar H: Observations on Malaria in Pregnancy. Journal of Obstetrics and Gynaecology India. 2004, 54 (5): 456-59.
- Tagbor H, Bruce J, Browne E, Randal A, Greenwood B, Chandramohan D: Efficacy, safety, and tolerability of amodiaquine plus sulphadoxine-pyrimethamine used alone or in combination for malaria treatment in pregnancy: a randomised trial. The Lancet. 2006, 368 (9544): 1349-1356. 10.1016/S0140-6736(06)69559-7. · DOI · Paper page
- Sharma SK, Tyagi PK, Padhan K, Upadhyay AK, Haque MA, Nanda N, Joshi H, Biswas S, Adak T, Das BS, Chauhan VS, Chitnis CE, Subbarao SK: Epidemiology of malaria transmission in forest and plain ecotype villages of Sundargarh District Orissa, India. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2006, 100: 917-925. 10.1016/j.trstmh.2006.01.007. · DOI
- Biswas RKKAK: Fertility Profile of a primitive tribe, Madhya Pradesh. Anthropologist. 2003, 5 (3): 161-167. · DOI
- Bhat PNM: Maternal Mortality in India: An update. Studies in Family Planning. 2002, 33 (3): 227-236. 10.1111/j.1728-4465.2002.00227.x. · DOI
- Balgir RS: Do Tribal Communities show an inverse relationship between sickle cell disorders and glucose-6-phosphate dehydrogenase deficiency in malaria endemic areas of Central-Eastern India?. Journal of Comparative Human Biology. 2006, 57: 163-176. 10.1016/j.jchb.2006.01.003. · DOI
- Directorate of National Vector Borne Disease Control Programme: National Drug Policy. 2007, M.o.H.a.F. Welfare, New Delhi, India
- Luxemburger C, McGready R, Kham1 A, Morison L, Cho T, Chongsuphajaisiddhi T, White NJ, Nosten F: Effects of Malaria During Pregnancy on Infant Mortality in an Area of Low Malaria Transmission. American Journal of Epidemiology. 2001, 154 (5): 459-465. 10.1093/aje/154.5.459. · DOI · Paper page
- Desai M, Kuile FT, Nosten F, McGready R, Asamoa K, Brabin B, Newmanal R: Epidemiology and burden of malaria in pregnancy. Lancet Infectious Disease. 2007, 7: 93-104. 10.1016/S1473-3099(07)70021-X. · DOI · Paper page
Cited by
Sorted by citations
Estimating the Global Clinical Burden of Plasmodium falciparum Malaria in 2007
Hay, S. I., Okiro, E. A., Gething, P. W., Patil, A. P., Tatem, A. J., Guerra, C. A., & Snow, R. W. (2010) · PLoS Medicine · doi:10.1371/journal.pmed.1000290 · Cited by 374
Takem, E. N., & D'Alessandro, U. (2013) · Mediterranean Journal of Hematology and Infectious Diseases · doi:10.4084/mjhid.2013.010 · Cited by 185
Hidden burden of malaria in Indian women
Sharma, V. P. (2009) · Malaria Journal · doi:10.1186/1475-2875-8-281 · Cited by 24
Metadata
- Authors
- Diamond-Smith, N., Singh, N., Gupta, R. D., Dash, A., Thimasarn, K., Campbell, O. M., & Chandramohan, D.
- Affiliations
- National Institute of Malaria Research (IN)
- World Health Organization Regional Office for South-East Asia (IN)
- London School of Hygiene & Tropical Medicine (GB)
- Venue
- Malaria Journal
- Published
- 2009-02-12
- Volume
- 8
- Issue
- 1
- Pages
- 24-24
- ISSN
- 1475-2875 (ISSN-L)
- PMC
- PMC2647551
- OpenAlex
- W2170368528
- Cited by
- 27
- References
- 0
- Citations by year
- 2025: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 2 · 2019: 2 · 2016: 1 · 2015: 1 · 2014: 1 · 2013: 5 · 2012: 3
- FWCI
- 3.36
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Malaria Journal (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Greater South Information System
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Global Maternal and Child Health
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- malaria in pregnancy, disease burden estimation, maternal mortality, fetal death, tribal women, forest environment, case fatality rate, pregnancy prevalence
- MeSH terms
- Animals, Female, Fetal Death, Humans, India, Infant, Newborn, Malaria, Maternal Mortality, Monte Carlo Method, Pregnancy, Pregnancy Outcome, Risk Factors, Rural Population, Pregnancy Complications, Parasitic, Prevalence, Cost of Illness, Parasitemia
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
