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Regulation of ovulation rate in mammals: contribution of sheep genetic models
Open accessAbstract
Ovarian folliculogenesis in mammals from the constitution of primordial follicles up to ovulation is a reasonably well understood mechanism. Nevertheless, underlying mechanisms that determine the number of ovulating follicles were enigmatic until the identification of the fecundity genes affecting ovulation rate in sheep, bone morphogenetic protein-15 (BMP-15), growth and differentiation factor-9 (GDF-9) and BMP receptor-1B (BMPR-1B). In this review, we focus on the use of these sheep genetic models for understanding the role of the BMP system as an intra-ovarian regulator of follicular growth and maturation, and finally, ovulation rate.
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Cited by
Regulation of folliculogenesis and the determination of ovulation rate in ruminants
Scaramuzzi, R. J., Baird, D. T., Campbell, B. K., Driancourt, M.-A., Dupont, J., Fortune, J. E., Gilchrist, R. B., Martin, G. B., McNatty, K. P., McNeilly, A. S., et al. (2011) · Reproduction, Fertility and Development · doi:10.1071/rd09161 · Cited by 310
Self-citationMonniaux, D., Michel, P., Postel, M., & Clément, F. (2016) · Biology of the Cell · doi:10.1111/boc.201500087 · Cited by 36
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Metadata
- Authors
- Fabre, S., Pierre, A., Mulsant, P., Bodin, L., Di Pasquale, E., Persani, L., Monget, P., & Monniaux, D.
- Venue
- Reproductive Biology and Endocrinology
- Published
- 2006-04-12
- Volume
- 4
- Issue
- 1
- Pages
- 20-20
- ISSN
- 1477-7827 (ISSN-L)
- OpenAlex
- W1656109000
- Cited by
- 232
- References
- 0
- FWCI
- 4.66
- Type
- journal article
- Language
- en
- Open access
- gold
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- Fabre, S., Pierre, A., Mulsant, P., Bodin, L., Di Pasquale, E., Persani, L., Monget, P., & Monniaux, D. (2006). Regulation of ovulation rate in mammals: contribution of sheep genetic models. Reproductive Biology and Endocrinology. https://doi.org/10.1186/1477-7827-4-20
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