The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Maternal exposure to nanoparticulate titanium dioxide during the prenatal period alters gene expression related to brain development in the mouse
Open accessAbstract
Background: Nanotechnology is developing rapidly throughout the world and the production of novel man-made nanoparticles is increasing, it is therefore of concern that nanomaterials have the potential to affect human health. The purpose of this study was to investigate the effects of maternal exposure to nano-sized anatase titanium dioxide (TiO 2) on gene expression in the brain during the developmental period using cDNA microarray analysis combined with Gene Ontology (GO) and Medical Subject Headings (MeSH) terms information. Results: Analysis of gene expression using GO terms indicated that expression levels of genes associated with apoptosis were altered in the brain of newborn pups, and those associated with brain development were altered in early age. The genes associated with response to oxidative stress were changed in the brains of 2 and 3 weeks old mice. Changes of the expression of genes associated with neurotransmitters and psychiatric diseases were found using MeSH terms. Conclusion: Maternal exposure of mice to TiO 2 nanoparticles may affect the expression of genes related to the development and function of the central nervous system.
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Fetal nutrition and cardiovascular disease in adult life
Barker, D. J. P., Godfrey, K. M., Gluckman, P. D., Harding, J. E., Owens, J. A., & Robinson, J. S. (1993) · The Lancet · doi:10.1016/0140-6736(93)91224-a · Cited by 2,753
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A review of biomass burning: Emissions and impacts on air quality, health and climate in China
Chen, J., Li, C., Ristovski, Z., Milic, A., Gu, Y., Islam, M. S., Wang, S., Hao, J., Zhang, H., He, C., et al. (2017) · Science of The Total Environment · doi:10.1016/j.scitotenv.2016.11.025 · Cited by 1,262
Review of the health effects of wildland fire smoke on wildland firefighters and the public
Adetona, O., Reinhardt, T. E., Domitrovich, J., Broyles, G., Adetona, A. M., Kleinman, M. T., Ottmar, R. D., & Naeher, L. P. (2016) · Inhalation Toxicology · doi:10.3109/08958378.2016.1145771 · Cited by 305
Reproductive and developmental toxicity studies of manufactured nanomaterials
Ema, M., Kobayashi, N., Naya, M., Hanai, S., & Nakanishi, J. (2010) · Reproductive Toxicology · doi:10.1016/j.reprotox.2010.06.002 · Cited by 269
Particle toxicology and health - where are we?
Riediker, M., Zink, D., Kreyling, W., Oberdörster, G., Elder, A., Graham, U., Lynch, I., Duschl, A., Ichihara, G., Ichihara, S., et al. (2019) · Particle and Fibre Toxicology · doi:10.1186/s12989-019-0302-8 · Cited by 237
Self-citationHougaard, K. S., Jackson, P., Jensen, K. A., Sloth, J. J., Löschner, K., Larsen, E. H., Birkedal, R. K., Vibenholt, A., Boisen, A.-M. Z., Wallin, H., et al. (2010) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-7-16 · Cited by 191
Metadata
- Authors
- Shimizu, M., Tainaka, H., Oba, T., Mizuo, K., Umezawa, M., & Takeda, K.
- Venue
- Particle and Fibre Toxicology
- Published
- 2009-07-29
- Volume
- 6
- Issue
- 1
- Pages
- 20-20
- ISSN
- 1743-8977 (ISSN-L)
- OpenAlex
- W2169282855
- Cited by
- 272
- References
- 1
- FWCI
- 10.85
- Type
- journal article
- Language
- en
- Open access
- gold
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- Shimizu, M., Tainaka, H., Oba, T., Mizuo, K., Umezawa, M., & Takeda, K. (2009). Maternal exposure to nanoparticulate titanium dioxide during the prenatal period alters gene expression related to brain development in the mouse. Particle and Fibre Toxicology. https://doi.org/10.1186/1743-8977-6-20
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