The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Early diagnosis to enable early treatment of pre-osteoarthritis
Open accessAbstract
Osteoarthritis is a prevalent and disabling disease affecting an increasingly large swathe of the world population. While clinical osteoarthritis is a late-stage condition for which disease-modifying opportunities are limited, osteoarthritis typically develops over decades, offering a long window of time to potentially alter its course. The etiology of osteoarthritis is multifactorial, showing strong associations with highly modifiable risk factors of mechanical overload, obesity and joint injury. As such, characterization of pre-osteoarthritic disease states will be critical to support a paradigm shift from palliation of late disease towards prevention, through early diagnosis and early treatment of joint injury and degeneration to reduce osteoarthritis risk. Joint trauma accelerates development of osteoarthritis from a known point in time. Human joint injury cohorts therefore provide a unique opportunity for evaluation of pre-osteoarthritic conditions and potential interventions from the earliest stages of degeneration. This review focuses on recent advances in imaging and biochemical biomarkers suitable for characterization of the pre-osteoarthritic joint as well as implications for development of effective early treatment strategies.
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Cited by
The Role of ACL Injury in the Development of Posttraumatic Knee Osteoarthritis
Friel, N. A., & Chu, C. R. (2013) · Clinics in Sports Medicine · doi:10.1016/j.csm.2012.08.017 · Cited by 287
Self-citationOsteoarthritis: From Palliation to Prevention: AOA Critical Issues
Chu, C. R., Millis, M. B., & Olson, S. A. (2014) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.m.01209 · Cited by 100
Self-citationLugo, J. P., Saiyed, Z. M., Lau, F. C., Molina, J. P. L., Pakdaman, M. N., Shamie, A. N., & Udani, J. K. (2013) · Journal of the International Society of Sports Nutrition · doi:10.1186/1550-2783-10-48 · Cited by 82
Shultz, S. J., Schmitz, R. J., Cameron, K. L., Ford, K. R., Grooms, D. R., Lepley, L. K., Myer, G. D., & Pietrosimone, B. (2019) · Journal of Athletic Training · doi:10.4085/1062-6050-54.084 · Cited by 44
Metadata
- Authors
- Chu, C. R., Williams, A. A., Coyle, C. H., & Bowers, M. E.
- Venue
- Arthritis Research & Therapy
- Published
- 2012
- Volume
- 14
- Issue
- 3
- Pages
- 212
- ISSN
- 1478-6354 (ISSN-L)
- OpenAlex
- W1990354342
- Cited by
- 253
- References
- 55
- FWCI
- 7.62
- Type
- journal article
- Language
- en
- Open access
- gold
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- Chu, C. R., Williams, A. A., Coyle, C. H., & Bowers, M. E. (2012). Early diagnosis to enable early treatment of pre-osteoarthritis. Arthritis Research & Therapy. https://doi.org/10.1186/ar3845
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
