Genomic Scars as Biomarkers of Homologous Recombination Deficiency and Drug Response in Breast and Ovarian Cancers

Watkins, Johnathan A, Irshad, Sheeba, Grigoriadis, Anita, Tutt, Andrew NJ·2014·Breast Cancer Research

DOI 10.1186/bcr3670

Cited by (327)

Items 301–327 of 327

Additional file 2 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhaï, Silvia Mihaela Ilie, Audrey Hennequin et al. · 2022 · Figshare
Additional file 7 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhaï, Silvia Mihaela Ilie, Audrey Hennequin et al. · 2022 · Figshare
Additional file 9 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhaï, Silvia Mihaela Ilie, Audrey Hennequin et al. · 2022 · Figshare
Additional file 11 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhaï, Silvia Mihaela Ilie, Audrey Hennequin et al. · 2022 · Figshare
Additional file 1 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhaï, Silvia Mihaela Ilie, Audrey Hennequin et al. · 2022 · Figshare
Additional file 10 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Kaderbhai, Courèche, Silvia Mihaela Ilie, Audrey Hennequin et al. · 2022 · Figshare
Additional file 1 of Mutations of TP53 and genes related to homologous recombination repair in breast cancer with germline BRCA1/2 mutations
Kim, Jinyong, Kyeonghun Jeong, Jun, Hyeji, Kim, Kwangsoo, Jeong Mo Bae, Myung Geun Song, Hanbaek Yi, Park, Songyi, 우고운, Lee, Dae-Won et al. · 2024 · Figshare
Additional file 12 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhaï, Silvia Mihaela Ilie, Audrey Hennequin et al. · 2022 · Figshare
Additional file 8 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Kaderbhai, Courèche, Silvia Mihaela Ilie, Audrey Hennequin et al. · 2022 · Figshare
Additional file 1 of GSA: an independent development algorithm for calling copy number and detecting homologous recombination deficiency (HRD) from target capture sequencing
Chen, Dongju, Shao, Minghui, Meng, Pei, Wang, Chunli, Li, Qi, Cai, Yuhang, Song, Chengcheng, Wang, Xi, Shi, Taiping · 2021 · Figshare
Additional file 2 of expHRD: an individualized, transcriptome-based prediction model for homologous recombination deficiency assessment in cancer
Lee, Jae Jun, Hyun Ju Kang, Kim, Donghyo, Si On Lim, Stephanie S. Kim, Kim, Gahyun, Kim, Sanguk, Lee, Jin-Ku, JINHO KIM · 2024 · Figshare
Additional file 6 of Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhaï, Silvia Mihaela Ilie, Audrey Hennequin et al. · 2022 · Figshare
Additional file 1 of expHRD: an individualized, transcriptome-based prediction model for homologous recombination deficiency assessment in cancer
Lee, Jae Jun, Hyun Ju Kang, Kim, Donghyo, Si On Lim, Kim, Stephanie S., Kim, Gahyun, Kim, Sanguk, Lee, Jin-Ku, JINHO KIM · 2024 · Figshare
Etude des modifications épigénétiques en fonction de l'agressivité du cancer sporadique du sein : l'implication de l'histone désacétylase SIRT1 dans la progression tumorale
K. Rifai · 2018
Optimisation de la chimio-radiothérapie à base de gemcitabine par un inhibiteur de poly-ADP ribose polymérase dans les cancers du pancréas
Waïsse Waïssi · 2019
Médecine personnalisée dans le cancer de l'endomètre : développement de nouveaux biomarqueurs pronostiques et théranostiques
Guillaume Beinse · 2022 · theses.fr (ABES)
The effect of PARP inhibitor-based targeted therapy on BRCA-mutated ovarian cancer: systematic literature review
Dwi Andhika Panjarwanto, Putri Nabila, Leony Octavia, I Wayan Agung Indrawan, Rudi Priyo Utomo, Adin Yan Permana, Kaspan, I Gde Hary Eka Adnyana, Raden Mohamad Javier, Muhammad Zidan Habibullah Akbar · 2026 · Frontiers in Oncology
Exploring the somatic mutational landscape of ovarian cancer in Estonia
Mikk Tooming, Kadri Rekker, Kadri Toome, Laura Roht, Piret Laidre, Olga Fjodorova, Ustina Šamarina, Sander Pajusalu, Mihkel Ilisson, Pilleriin Peets et al. · 2026 · Acta Oncologica
Development and validation of an epigenetic score for homologous recombination deficiency based on genome-wide DNA methylation profiling in ovarian cancer
Hao Zhu, Wanhong He, Sufen Zhang, Haijing Cao, Ming Shen, Xiaofeng Wan, Qihan Wu · 2026 · Gene Reports
Performance Assessment of a Locally Semi-Automated NGS-Based Workflow for Homologous Recombination Deficiency Testing in High-Grade Serous Ovarian Carcinoma
Maria Colomar-Roig, Lara Navarro, Javier Megías, M. Nunez Abad, Esther Roselló-Sastre, Núria Santonja-López, Teresa San‐Miguel · 2026 · Biomedicines
Comprehensive comparison of homologous recombination deficiency predictors in early-stage triple-negative breast cancer
Deborah F. Nacer, Srinivas Veerla, Iñaki Sasiain, Jari Häkkinen, Johan Vallon‐Christersson, Maria Rossing, Serena Nik‐Zainal, Anders Edsjö, Johan Staaf · 2026 · Breast Cancer Research
Somatic BRCA alterations in breast cancer are associated with distinct biological and clinical patterns according to germline BRCA status
Masanori Oshi, Kei Kawashima, Makoto Sugimori, A. Yamada, Z. Shah, Kenan Onel, I. Endo, K. Takabe · 2026 · ESMO Open
Homologous recombination deficiency testing implementation in the routine clinical setting: real-life experience and lessons learned
Paula Romero-Lozano, Marina Gómez-Rey, María Vila-Casadesús, A. Martin, G. Buono, V. Bach, A. Onieva, M. Ricart, N. Deltiempo, E Castillo et al. · 2026 · ESMO Open
Association of HRD Score With Efficacy of Neoadjuvant Short‐Course Radiotherapy Plus Sequential Chemoimmunotherapy in pMMR Locally Advanced Rectal Cancer
Xin Ran, He Xiao, Peng Zhou, Juan He, Meng-Yuan Si, Xiu-Qiong Chen, Xiao-Na Su, Zhuo Chen, Jia Du, Xiao-Yan Dai et al. · 2026 · Cancer Reports
Alternative Splicing of Homologous Recombination Genes Is Associated with Homologous Recombination Deficiency and Immunoregulatory Phenotypes in Breast Cancer
Ahmed Basudan, Yazeed Alshuweishi, Hamood AlSudais, Mohammad A. Alfhili · 2026 · Biomedicines
When Genomic Scars Outlive Genomic Vulnerability: Dynamic DNA Damage Repair in Cancer Evolution and Therapeutic Resistance
Alessandro Ottaiano, Francesco Sabbatino, Anna Chiara Carratù, Marco Cascella, Antonio Alci Barone, Francesco Perri, Andrea Belli, Alfredo Columbro, Francesco Izzo, Mariafelicia Valeriani et al. · 2026 · Genes
Application of semidefinite programming approach for detection of genomic copy number variations from peripheral blood in ovarian cancer
Michael Kalab, Arunabh Sharma, Anastasia Klopf, Lena Wahl, Huy Duc Le, Nina Hedemann, Annika Bräuer, David Holthaus, Christoph Rogmans, Dirk Bauerschlag et al. · 2026 · Frontiers in Oncology