The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Frailty and post-operative outcomes in older surgical patients: a systematic review
Open accessAbstract
BACKGROUND: As the population ages, increasing numbers of older adults are undergoing surgery. Frailty is prevalent in older adults and may be a better predictor of post-operative morbidity and mortality than chronological age. The aim of this review was to examine the impact of frailty on adverse outcomes in the 'older old' and 'oldest old' surgical patients. METHODS: A systematic review was undertaken. Electronic databases from 2010 to 2015 were searched to identify articles which evaluated the relationship between frailty and post-operative outcomes in surgical populations with a mean age of 75 and older. Articles were excluded if they were in non-English languages or if frailty was measured using a single marker only. Demographic data, type of surgery performed, frailty measure and impact of frailty on adverse outcomes were extracted from the selected studies. Quality of the studies and risk of bias was assessed by the Epidemiological Appraisal Instrument. RESULTS: Twenty-three studies were selected for the review and they were assessed as medium to high quality. The mean age ranged from 75 to 87 years, and included patients undergoing cardiac, oncological, general, vascular and hip fracture surgeries. There were 21 different instruments used to measure frailty. Regardless of how frailty was measured, the strongest evidence in terms of numbers of studies, consistency of results and study quality was for associations between frailty and increased mortality at 30 days, 90 days and one year follow-up, post-operative complications and length of stay. A small number of studies reported on discharge to institutional care, functional decline and lower quality of life after surgery, and also found a significant association with frailty. CONCLUSION: There was strong evidence that frailty in older-old and oldest-old surgical patients predicts post-operative mortality, complications, and prolonged length of stay. Frailty assessment may be a valuable tool in peri-operative assessment. It is possible that different frailty tools are best suited for different acuity and type of surgical patients. The association between frailty and return to pre-morbid function, discharge destination, and quality of life after surgery warrants further research.
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Cites
Frailty in Older Adults: Evidence for a Phenotype
Fried, L. P., Tangen, C. M., Walston, J., Newman, A. B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W. J., Burke, G., et al. (2001) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/56.3.m146 · Cited by 24,907
A global clinical measure of fitness and frailty in elderly people
Rockwood, K. (2005) · Canadian Medical Association Journal · doi:10.1503/cmaj.050051 · Cited by 8,968
Prevalence and 10‐Year Outcomes of Frailty in Older Adults in Relation to Deficit Accumulation
Song, X., Mitnitski, A., & Rockwood, K. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.02764.x · Cited by 1,104 · cited 1×
“logical systems, is a better predictor of mortality and morbidity than chronological age [4, 5].”
BackgroundGreen, P., Woglom, A. E., Genereux, P., Daneault, B., Paradis, J.-M., Schnell, S., Hawkey, M., Maurer, M. S., Kirtane, A. J., Kodali, S., et al. (2012) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2012.06.011 · Cited by 473
Schoenenberger, A. W., Stortecky, S., Neumann, S., Moser, A., Juni, P., Carrel, T., Huber, C., Gandon, M., Bischoff, S., Schoenenberger, C.-M., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/ehs304 · Cited by 299
Patel, K. V., Brennan, K. L., Brennan, M. L., Jupiter, D. C., Shar, A., & Davis, M. L. (2014) · Clinical Orthopaedics & Related Research · doi:10.1007/s11999-013-3334-7 · Cited by 157
Cited by
Development of a novel frailty index to predict mortality in patients with end‐stage liver disease
Lai, J. C., Covinsky, K. E., Dodge, J. L., Boscardin, W. J., Segev, D. L., Roberts, J. P., & Feng, S. (2017) · Hepatology · doi:10.1002/hep.29219 · Cited by 556
Alive and at home: five-year outcomes in older adults following emergency general surgery
Guttman, M. P., Tillmann, B. W., Nathens, A. B., Saskin, R., Bronskill, S. E., Huang, A., & Haas, B. (2021) · Journal of Trauma and Acute Care Surgery · doi:10.1097/ta.0000000000003018 · Cited by 19
Yang, F., Yuan, Y., Liu, W., Tang, C., He, F., Chen, D., Xiong, J., Huang, G., & Qian, K. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1411353 · Cited by 19
Metadata
- Authors
- Lin, H.-S., Watts, J. N., Peel, N. M., & Hubbard, R. E.
- Venue
- BMC Geriatrics
- Published
- 2016-08-31
- Volume
- 16
- Issue
- 1
- Pages
- 157-157
- ISSN
- 1471-2318 (ISSN-L)
- OpenAlex
- W2507525628
- Cited by
- 1,121
- References
- 6
- FWCI
- 6.19
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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