Co-morbidities of mental disorders and chronic physical diseases in developing and emerging countries: a meta-analysis
Open accessAbstract
BACKGROUND: As the data on the association of mental disorders and chronic physical diseases in developing and emerging countries is heterogeneous, this study aims to produce the first meta-analysis of these comorbidities. METHODOLOGY: The meta-analysis protocol was registered in PROSPERO (N°CRD42017056521) and was performed in accordance with PRISMA guidelines. Initially, an article search was conducted on Medline, Embase, Lilacs and the Institut d'Epidémiologie et de Neurologie Tropicale database [Institute of Epidemiology and Tropical Neurology], as well as manually, with no restriction on language or date focusing on mental disorders, chronic diseases and neurotropic diseases. Two independent investigators assessed the quality of the studies which met the inclusion criteria using the Downs and Black assessment grid. The pooled estimates were calculated out using a random-effects method with CMA software Version 3.0. A meta-regression was then performed, and the significance level was set at 0.05. RESULTS: Of the 2604 articles identified, 40 articles involving 21,747 subjects met the inclusion criteria for co-morbidities between mental disorders and chronic physical diseases. Thirty-one articles were included in the meta-analysis of prevalence studies and 9 articles in that of the analytical studies. The pooled prevalence of mental disorders in patients with chronic physical diseases was 36.6% (95% CI, 31.4-42.1) and the pooled odds ratio was 3.1 (95% CI, 1.7-5.2). There was heterogeneity in all the estimates and in some cases, this was explained by the quality of the studies. CONCLUSION: Some estimates regarding the prevalence of mental disorders in people with chronic physical diseases living in developing and emerging countries were similar to those in developed countries. Mental disorders are a burden in these countries. In order to respond effectively and efficiently to the morbidity and mortality associated with them, mental health care could be integrated with physical care.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Physical-psychological comorbidity and multimorbidity of CIDs are common.
“Findings are clinically relevant to the physical rehabilitation field given that physical-psychological comorbidity and multimorbidity of CIDs are common (Daré et al., 2019; Tinetti et al., 2012).”
From Attachment insecurity predicts outcomes in an ACT-CBT group therapy for adults in a physical rehabilitation centre (2022) · cites this paper as Daré et al., 2019
The Background says mental disorders are often associated with one or more chronic physical diseases, and the Results report a pooled prevalence of 36.6% for mental disorders among patients with chronic physical diseases in developing and emerging countries. This supports the general claim that physical–psychological comorbidity is common, but the paper does not establish how common multimorbidity is specifically among people with CIDs. The supplied copy gives section labels but no page numbers. (LLM, conf=0.82)
Experimental — accuracy not yet measuredCID-psychological comorbidity is common and multimorbidity of CIDs is the norm.
“CID-psychological comorbidity is common (Daré et al., 2019) and multimorbidity of CIDs is the norm (Tinetti, Fried, & Boyd, 2012)”
From Attachment insecurity predicts outcomes in an ACT-CBT group therapy for adults in a physical rehabilitation centre (2022) · cites this paper as Daré et al., 2019
Symptoms of emotional difficulties such as depressed mood and anxiety are common among individuals living with a CID.
“Symptoms of emotional difficulties, such as depressed mood and anxiety, are common experiences among individuals living with a CID (Daré et al., 2019)”
From Attachment insecurity predicts outcomes in an ACT-CBT group therapy for adults in a physical rehabilitation centre (2022) · cites this paper as Daré et al., 2019
The medical care provided to people with psychiatric disorders is lower than that received by those without mental disorders.
“the medical care provided to people with psychiatric disorders is lower than that received by those without mental disorders:21”
From <p>Pain and Evil: From Local Nociception to Misery Following Social Harm</p> (2020) · cites this paper as [21]
In low- and middle-income countries, approximately 80% of people with severe mental disorders do not receive treatment.
“in low- and middle-income countries, approximately 80% of people with severe mental disorders do not receive treatment.”
From <p>Pain and Evil: From Local Nociception to Misery Following Social Harm</p> (2020) · cites this paper as [21]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
The citation lists haven’t been fetched yet
References 94 · Cited by 197
Research works printed but not linked: 3
- [2]Thornicroft G Votruba N Baingana F Bhugra D Eaton J Goetzke K Gureje O Ivbijaro G Lamichhane J Lund C Millennium development goals: lessons for global mental health Epidemiol Psychiatr Sci 2014 24 458 460 PMC8367354 25952332
- [31]Moher D., Shamseer L., Ghersi D., Liberati A., Petticrew M., Shekelle P., et al. PRISMA for systematic review protocols (PRISMA-P). http://prisma-statement.org/Extensions/Protocols.aspx. Accessed 30 Oct 2016.
- [39]Borenstein M Larry VH Julian PTH Hannah RR Introduction to forest plots 2009 Oxford Wiley
- Authors
- Daré, L. O., Bruand, P.-E., Gérard, D., Marin, B., Lameyre, V., Boumédiène, F., & Preux, P.-M.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Sanofi (France) (FR)
- Corresponding author
- Daré, Labanté Outcha
- Venue
- BMC Public Health
- Published
- 2019-03-13
- Volume
- 19
- Issue
- 1
- Pages
- 304-304
- ISSN
- 1471-2458 (ISSN-L)
- PMC
- PMC6417021
- OpenAlex
- W2938166958
- Cited by
- 197
- References
- 94
- Citations by year
- 2026: 21 · 2025: 33 · 2024: 27 · 2023: 35 · 2022: 46 · 2021: 26 · 2020: 6 · 2019: 3
- FWCI
- 3.16
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Public Health (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- HAL (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Sanofi
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- mental illness, chronic physical illness, comorbidities, prevalence, developing countries, emerging countries
- MeSH terms
- Mental Disorders, Chronic Disease, Developing Countries, Humans, Comorbidity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
