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Cited by 60dental development and anomaliesDental Health and Care UtilizationDental materials and restorations

Oral health-related quality of life before and after crown therapy in young patients with amelogenesis imperfecta

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Pousette Lundgren, Gunilla, Karsten, Agneta, Dahllöf, Göran·2015·Health and Quality of Life Outcomes
DOI 10.1186/s12955-015-0393-3PMC PMC4676094
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Abstract

BACKGROUND: Amelogenesis imperfecta (AI) is a rare, genetically determined defect in enamel mineralization associated with poor esthetics and dental sensitivity. Because the condition is associated with negative social outcomes, this study evaluated oral health-related quality of life (OHRQoL), dental fear, and dental beliefs before and after early prosthetic crown therapy for AI during adolescence. METHODS: The study included 69 patients with AI, aged 6-25 yr: 33 males and 36 females (mean age 14.5 ± 4.3); healthy controls (n = 80), patients with cleft lip and palate (CLP; n = 30), and patients with molar incisor hypomineralization (MIH; n = 39). All matched in age and gender, and all but the CLP group insocioeconomic area. Patients completed three questionnaires measuring OHRQoL (OHIP-14), dental fear (CFSS-DS), and dental beliefs (DBS-R). Twenty-six patients with severe AI between ages 9 and 22 yr received crown therapy and completed the questionnaires twice: before and after therapy. RESULTS: OHIP-14 scores were significantly higher among patients with AI (7.0 ± 6.7), MIH (6.8 ± 7.6) and CLP (13.6 ± 12.1) than healthy controls (1.4 ± 2.4) (p < 0.001). After crown therapy, quality of life problems in the 26 patients with severe AI decreased significantly, from 7.8 ± 6.1 to 3.0 ± 4.8 (p < 0.001). Early prosthetic therapy did not increase dental fear or negative attitudes toward dental treatment. CONCLUSIONS: OHRQoL increased after early crown therapy in patients with severe AI. Therapy did not increase dental fear or negative attitudes toward dental treatment.

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  • Studies in patients with AI have shown that the early use of indirect restorations in the second decade of life is associated with positive effects.

    “Interestingly, studies in patients with AI have shown that the early use of indirect restorations in the second decade of life is associated with positive effects (e.g., Pousette Lundgren et al. 2015; Klink et al. 2018; Lundgren et al. 2018) (Table 1).”

    From Dental Management of Genetic Dental Disorders: A Critical Review (2025) · cites this paper as Pousette Lundgren et al. 2015

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References 55 · Cited by 60

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Authors
Pousette Lundgren, G., Karsten, A., & Dahllöf, G.
Affiliations
Karolinska Institutet (SE)
ORCID
Venue
Health and Quality of Life Outcomes
Publisher
Springer Science and Business Media LLC
Published
2015-12
Volume
13
Issue
1
Pages
197-197
ISSN
1477-7525 (ISSN-L)
DOI
10.1186/s12955-015-0393-3
PMC
PMC4676094
OpenAlex
W2194380352
Cited by
60
References
55
Citations by year
2026: 4 · 2025: 5 · 2024: 8 · 2023: 6 · 2022: 9 · 2021: 4 · 2020: 4 · 2019: 9 · 2018: 5 · 2017: 2 · 2016: 3 · 2015: 1
FWCI
1.59
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Health and Quality of Life Outcomes (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
  • Public dental service,County of Dalarna
  • Center for clinical research, County of Dalarna
  • Karoliniska Institutet, Emelie och Gotthard Thourens fond
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › dental development and anomalies
  • Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
  • Health Sciences › Dentistry › Orthodontics › Dental materials and restorations
Keywords
amelogenesis imperfecta, oral health-related quality of life, dental crowns, dental anxiety, molar incisor hypomineralization, cleft lip and palate, enamel defects, adolescents, OHIP-14
MeSH terms
Adolescent, Adult, Amelogenesis Imperfecta, Child, Crowns, Dental Care, Female, Humans, Male, Oral Health, Psychosocial Deprivation, Quality of Life, Surveys and Questionnaires, Self Concept, Dental Anxiety, Young Adult

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