The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Corticosteroids or platelet-rich plasma injections for rotator cuff tendinopathy: a randomized clinical trial study
Open accessAbstract
Background: Studies evaluating the role of both corticosteroids and platelet-rich plasma (PRP) in the treatment of rotator cuff (RC) tendinopathies have been contradicting. We compared structural and clinical changes in RC muscles after corticosteroids and PRP injections. Methods: This is a randomized double-blind clinical trial. All individuals with diagnosis of RC tendinitis during 2014–2017 were considered. Individuals were randomly allocated to either receive PRP or corticosteroids. Overall, 3cc of PRP was injected within the subacromial joint and another 3cc was injected at the site of the tendon tear, under the guide of sonography. For the corticosteroid group, 1cc of Depo-medrol 40mg and 1cc of lidocaine (2%) was injected within the subacromial joint. Results: Overall, 58 patients entered the study. Comparison of pain, range of motion (ROM), Western Ontario RC (WORC), Disability of Arm-Hand-Shoulder (DASH) scores, and supraspinatus thickness showed significant improvement during follow-ups in both groups (p<0.05). During 3 months of follow-up, pain improvement was significantly better within the PRP group during (from 6.66±2.26 to 3.08±2.14 and 5.53±1.80 to 3.88±1.99, respectively; p=0.023). Regarding ROM, the PRP group had significant improvement in adduction (20.50°±8.23° to 28°±3.61° and 23.21°±7.09° to 28.46°±4.18° for the PRP and corticosteroid groups, respectively; p=0.011) and external rotation (59.66°±23.81° to 76.66°±18.30° and 57.14°±24.69° to 65.57°±26.39°, for the PRP and corticosteroid groups, respectively; p=0.036) compared to the corticosteroid group. Conclusion: We found that PRP renders similar results to that of corticosteroids in most clinical aspects among patients with RC tendinopathies; however, pain and ROM may show more significant improvement with the use of PRP. Considering that the use of corticosteroids may be contraindicated in some patients and may be associated with the risk of tendon rupture, we suggest the use of PRP in place of corticosteroid-based injections among patients with RC tendinopathy. Trial registration: Clinical trial registration code: IRCT201302174251N9
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“ROM increased.”
From Management of platelet-rich plasma and stem cells versus conventional treatments in musculoskeletal injury repair: A systematic review (2025) · cites this paper as [23]
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“VAS: PRP Δ-53.7%; ROM increased.”
From Management of platelet-rich plasma and stem cells versus conventional treatments in musculoskeletal injury repair: A systematic review (2025) · cites this paper as [23]
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“Another study on rotator cuff tendinopathy has demonstrated that PRP reduces V AS pain by 53.7% ( P = 0.023) and improves range of motion at 3months compared to corticosteroids. [23]”
From Management of platelet-rich plasma and stem cells versus conventional treatments in musculoskeletal injury repair: A systematic review (2025) · cites this paper as [23]
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“Another study on rotator cuff tendinopathy has demonstrated that PRP reduces V AS pain by 53.7% ( P = 0.023) and improves range of motion at 3months compared to corticosteroids. [23]”
From Management of platelet-rich plasma and stem cells versus conventional treatments in musculoskeletal injury repair: A systematic review (2025) · cites this paper as [23]
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Gummesson, C., Atroshi, I., & Ekdahl, C. (2003) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-4-11 · Cited by 1,130
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Measuring shoulder function: A systematic review of four questionnaires
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Kinesiology: Scientific Basis of Human Motion
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Cited by
Ballesta, F. J. G., Vásquez, L. N. A., Borbón, J. R., Leal, J. A. C., Agudelo, D. S. J., & Granados, J. P. A. (2025) · Journal of Musculoskeletal Surgery and Research · doi:10.25259/jmsr_402_2025
Metadata
- Authors
- Dadgostar, H., Fahimipour, F., Pahlevan Sabagh, A., Arasteh, P., & Razi, M.
- Affiliations
- Iran University of Medical Sciences (IR)
- Shiraz University of Medical Sciences (IR)
- Corresponding author
- Fahimipour, Farinaz
- Venue
- Journal of Orthopaedic Surgery and Research
- Published
- 2021-05-21
- Volume
- 16
- Issue
- 1
- Pages
- 333-333
- ISSN
- 1749-799X (ISSN-L)
- PMC
- PMC8139041
- OpenAlex
- W3161411817
- Cited by
- 64
- References
- 25
- Citations by year
- 2026: 9 · 2025: 20 · 2024: 12 · 2023: 15 · 2022: 8
- FWCI
- 8.22
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- creativecommons.org/licenses/by/4.0 (tdm)
- creativecommons.org/licenses/by/4.0 (vor)
- Locations
- Journal of Orthopaedic Surgery and Research (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Iran University of Medical Sciences
- Topics
- Health Sciences › Medicine › Surgery › Shoulder Injury and Treatment
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Tendon Structure and Treatment
- Health Sciences › Dentistry › Periodontics › Periodontal Regeneration and Treatments
- Keywords
- rotator cuff tendinopathy, platelet-rich plasma, corticosteroid injection, rotator cuff tendinitis, shoulder pain, shoulder range of motion, subacromial injection, DASH score, rotator cuff repair, treatment comparison, ultrasound-guided injection, lidocaine, methylprednisolone acetate, rotator cuff muscles
- MeSH terms
- Rotator Cuff Injuries, Contraindications, Drug, Adrenal Cortex Hormones, Aged, Double-Blind Method, Female, Follow-Up Studies, Humans, Male, Middle Aged, Injections, Intralesional, Range of Motion, Articular, Treatment Outcome, Rotator Cuff, Platelet-Rich Plasma
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- CoChat. (2026). Citation check: Corticosteroids or platelet-rich plasma injections for rotator cuff tendinopathy: a randomized clinical trial study. https://app.cochat.ai/papers/10.1186/s13018-021-02470-x
- The paper
- Dadgostar, H., Fahimipour, F., Pahlevan Sabagh, A., Arasteh, P., & Razi, M. (2021). Corticosteroids or platelet-rich plasma injections for rotator cuff tendinopathy: a randomized clinical trial study. Journal of Orthopaedic Surgery and Research. https://doi.org/10.1186/s13018-021-02470-x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
