Mindfulness-based intervention for hypertension patients with depression and/or anxiety in the community: a randomized controlled trial
Open accessPublished version of a preprint
Abstract
Objective: To evaluate mindfulness-based intervention for hypertension with depression and/or anxiety. Methods: 10-week mindfulness-based intervention, including health education for hypertension, exclusively for the control group, was administered to the intervention group to assist sixty hypertension patients with depression/anxiety. Among them, the intervention group comprised 8 men and 22 women, with a mean age of 60.02 years and a mean duration of hypertension of 6.29 years. The control group consisted of 14 men and 16 women with a mean age of 57.68 years and a mean duration of hypertension of 6.32 years. The severity of depressive and/or anxiety symptoms was assessed using the 9-item Patient Health Questionnaire (PHQ-9) and the 7-item Generalized Anxiety Disorder scale (GAD-7), along with blood pressure (BP) measurements taken twice daily. The study utilized a self-made self-efficacy scale and awareness of physical and mental health to evaluate mental health and state. Results: The depression PHQ-9 or GAD-7 scores reduced by 21.1% or 17.8% in the mindfulness-based intervention group, compared to the control (Z = -2.040, P = 0.041) post 10-week period, suggesting significant reduction in anxiety/stress. These results were consistent with a reduction in systolic BP of 12.24 mm Hg (t = 6.041, P = 0.000). The self-efficacy score of the mindfulness intervention group significantly improved compared to the control (t = 7.818, P < 0.001), while the awareness of physical and mental health in the mindfulness intervention group significantly improved compared to the control (χ2 = 5.781, P = 0.016). Conclusion: Mindfulness-based, short-term focused interventions provide modest relief for depression and/or anxiety and are effective in lowering blood pressure and improving self-efficacy scores. Trial registration: Chinese Clinical Trial Registry, ChiCTR1900028258. Registered 16 December 2019, https://www.chictr.org.cn/showproj.html?proj=43627 .
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References 50 · Cited by 25
- Authors
- Zhang, H., Zhang, X., Jiang, X., Dai, R., Zhao, N., Pan, W., Guo, J., Fan, J., & Bao, S.
- Affiliations
- Gansu University of Traditional Chinese Medicine (CN)
- Gansu Provincial Center for Disease Control and Prevention (CN)
- Pingliang People's Hospital (CN)
- Corresponding author
- Guo, Jiaohong
- Fan, Jingchun
- Bao, Shisan
- Venue
- Trials
- Published
- 2024-05-02
- Volume
- 25
- Issue
- 1
- Pages
- 299-299
- ISSN
- 1745-6215 (ISSN-L)
- PMC
- PMC11529483
- OpenAlex
- W4396597537
- Cited by
- 25
- References
- 50
- Citations by year
- 2026: 13 · 2025: 11 · 2024: 1
- FWCI
- 12.53
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Trials (publishedVersion, cc-by)
- Research Square (acceptedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- 2020 Science and Technology Project of Chengguan District, Lanzhou (2020-2-11-16)
- Talent Introduction Program of Gansu University of Chinese Medicine, Gansu University of Chinese Medicine (2016YJRC-01)
- University Innovation Capacity Improvement Project in Gansu Province (2020B-153)
- the Innovation Fund of Postgraduate, Gansu University of Chinese Medicine (2021CX69)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- mindfulness-based interventions, hypertension, depression, anxiety, blood pressure reduction, self-efficacy, health awareness, community-based intervention, PHQ-9, GAD-7
- MeSH terms
- Aged, Anxiety, Blood Pressure, Depression, Female, Humans, Hypertension, Male, Mental Health, Middle Aged, Time Factors, Treatment Outcome, Self Efficacy, Mindfulness
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