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Cited by 45Trypanosoma species research and implicationsVector-borne infectious diseasesAnimal Disease Management and Epidemiology

Animal trypanosomosis in clinically healthy cattle of north Cameroon: epidemiological implications

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Mamoudou, Abdoulmoumini, Njanloga, Alexandre, Hayatou, Aliyou, Suh, Pierre Fongho, Achukwi, Mbunkah Daniel·2016·Parasites & Vectors
DOI 10.1186/s13071-016-1498-1PMC PMC4831123
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Abstract

BACKGROUND: The control of animal trypanosomosis consists, amongst other things, of the punctual treatment of new cases, primarily diagnosed by pastoralists on the basis of clinical signs. This practice suggests that many apparently healthy infected animals are left untreated. In this study animal trypanosomosis in clinically healthy zebu cattle was evaluated, the distribution of the vectors established and the epidemiological implications discussed. METHODS: In 2014 two cross-sectional surveys were carried out in the Cambeef ranch. A total of 866 blood samples were collected from cattle in different sites: 549 in the dry season and 317 in the rainy season. The blood samples were subjected to parasitological examination using the buffy coat method and to PCV determination. An entomological survey on animal trypanosomosis vectors was undertaken during tsetse flies caught were identified and the mid-gut of each living non-teneral tsetse fly was examined for infections using a microscope. RESULTS: An overall trypanosomosis prevalence of 9% was found in the cattle examined. There were significantly (P < 0.05) more trypanosome infected cattle in the dry season than the rainy season. Trypanosome-infected cattle had significantly (P < 0.05) lower Body Condition Scores (BCS) and Packed Cell Volumes (PCV) in the dry season than in the rainy season. Anemia was positively correlated with trypanosome infection. The likelihood for an animal to be parasitologically free of trypanosome infection was at least three times as high in the Gudali breed as compared with the white and red Fulani breeds. Species of trypanosomes identified were Trypanosoma vivax (73.23%), Trypanosoma congolense (15.49%) and Trypanosoma brucei (11.27%). A total of 390 tsetse flies and 103 tabanids were trapped. Two species of tsetse flies were identified: Glossina tachinoides (33.59%) and G. morsitans submorsitans (41%). Nine of the 194 non-teneral flies were infected with trypanosomes. CONCLUSION: Carriers of trypanosomes are present amongst apparently healthy cattle in the study site. Attempts to successfully reduce the population of reservoir trypanosomes within herds and control the disease will need to consider mass screening once every year and this should be associated with drug sensitivity tests.

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  • There is a difference in trypanosome-specific antiparasite antibody secreting cells in spleen and B cell activation between trypanotolerant and trypanosusceptible cattle.

    “There is a difference in trypanosome-specific antiparasite Ab secreting cells in spleen and B cell activation between trypanotolerant and trypanosusceptible cattle (La Greca et al., 2014; Mamoudou et al., 2016; Morrison et al., 2016).”

    From Identification of Candidate Signature Genes and Key Regulators Associated With Trypanotolerance in the Sheko Breed (2019) · cites this paper as Mamoudou et al., 2016

    The Discussion reports that Gudali cattle were more likely than white and red Fulani cattle to be free of detectable trypanosome infection and suggests this could indicate greater tolerance. The Methods describe blood-based parasite detection, and the Results report infection, anaemia, and body-condition measures. Searches for spleen antibody-secreting cells and B-cell activation found no passage addressing the immune-cell differences claimed. (LLM, conf=0.77)

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Authors
Mamoudou, A., Njanloga, A., Hayatou, A., Suh, P. F., & Achukwi, M. D.
Affiliations
  • University of Ngaoundéré (CM)
  • Université de Yaoundé I (CM)
  • Institut de Recherche Agricole pour le Développement (CM)
ORCID
Achukwi, Mbunkah Daniel
Venue
Parasites & Vectors
Publisher
Springer Science and Business Media LLC
Published
2016-04-13
Volume
9
Issue
1
Pages
206-206
ISSN
1756-3305 (ISSN-L)
DOI
10.1186/s13071-016-1498-1
PMC
PMC4831123
OpenAlex
W2340106514
Cited by
45
References
0
Citations by year
2026: 2 · 2025: 6 · 2024: 3 · 2023: 2 · 2022: 7 · 2021: 8 · 2020: 5 · 2019: 4 · 2018: 3 · 2017: 3 · 2016: 2
FWCI
3.75
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Parasites & Vectors (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Trypanosoma species research and implications
  • Life Sciences › Immunology and Microbiology › Parasitology › Vector-borne infectious diseases
  • Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Animal Disease Management and Epidemiology
Keywords
animal trypanosomiasis, Bos indicus, asymptomatic carriers, trypanosome prevalence, Glossina tachinoides, Glossina morsitans submorsitans, tsetse flies, Tabanidae, Trypanosoma vivax, Trypanosoma congolense, Trypanosoma brucei, seasonal variation, body condition score, anemia, hematocrit, cattle breeds, reservoir hosts, Cameroon, Fulani cattle
MeSH terms
Animals, Cameroon, Cattle, Cross-Sectional Studies, Female, Insect Vectors, Male, Seasons, Trypanosoma, Trypanosomiasis, Bovine, Tsetse Flies, Prevalence

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