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Cited by 95Medication Adherence and ComplianceBlood Pressure and Hypertension StudiesPharmacy and Medical Practices

Antihypertensive medication adherence and associated factors among adult hypertensive patients at Jimma University Specialized Hospital, southwest Ethiopia

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Asgedom, Solomon Weldegebreal, Atey, Tesfay Mehari, Desse, Tigestu Alemu·2018·BMC Research Notes
DOI 10.1186/s13104-018-3139-6PMC PMC5769214
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Abstract

BACKGROUND: Adherence to antihypertensive medications is a key component to control blood pressure levels. Poor adherence to these medications leads to the development of hypertensive complications and increase risk of cardiovascular events which in turn reduces the ultimate clinical outcome. The purpose of this study was to assess antihypertensive medication adherence and associated factors among adult hypertensive patients. A hospital-based cross-sectional study among adult hypertensive patients was conducted at hypertensive follow-up clinic of Jimma University Specialized Hospital from March 4, 2015 to April 3, 2015. A simple random sampling technique was used to select the study participants from the study population. The study patients were interviewed and their medical charts were reviewed using a pretested structured questionnaire. Adherence was assessed using Morisky Medication Adherence Scale-8 (MMAS-8) and MMAS-8 score less than 6 was considered as non-adherent and MMAS-8 score was ≥ 6 was declared as adherence. Factors associated with adherence were identified using binary and multivariate logistic regression analysis. Crude odds ratio, adjusted odds ratio (AOR) and 95% confidence interval of the odds ratio were calculated using SPSS version 21. Variables with p-value less than 0.05 were assumed as statistically significant factors. RESULTS: Among 280 hypertensive patients, 61.8% of the study participants were found to be adherent. More than half (53.2%) of the participants were males and the mean age of the participants was 55.0 ± 12.7 years. Co-morbidity (AOR = 0.083, 95% CI = 0.033-0.207, p < 0.001), alcohol intake (AOR = 0.011, 95% CI = 0.002-0.079, p < 0.001), getting medications freely (AOR = 0.020, 95% CI = 0.003-0.117, p < 0.001), and combination of antihypertensive medications (AOR = 0.32, 95% CI = 0.144-0.712, p < 0.005) were inversely associated with antihypertensive medication adherence. CONCLUSION: The adherence level to the prescribed antihypertensive medications was found to be sub-optimal according to the MMAS-8, and influenced by co morbidity, alcohol intake, self-purchasing of the medications and combination of antihypertensive medications.

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Authors
Asgedom, S. W., Atey, T. M., & Desse, T. A.
Affiliations
  • Mekelle University (ET)
  • Addis Ababa University (ET)
Corresponding author
Asgedom, Solomon Weldegebreal
ORCID
Venue
BMC Research Notes
Publisher
Springer Science and Business Media LLC
Published
2018-01-15
Volume
11
Issue
1
Pages
27-27
ISSN
1756-0500 (ISSN-L)
DOI
10.1186/s13104-018-3139-6
PMC
PMC5769214
OpenAlex
W2783433910
Cited by
95
References
36
Citations by year
2026: 6 · 2025: 22 · 2024: 17 · 2023: 10 · 2022: 13 · 2021: 13 · 2020: 7 · 2019: 6 · 2018: 1
FWCI
7.73
Type
journal article
Language
en
Update notices
correction (2018-08-16)
Open access
Licence
cc-by
Locations
  • BMC Research Notes (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • UTAS Research Repository (acceptedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Deakin Research Online (Deakin University) (submittedVersion)
  • Figshare (submittedVersion, cc-by)
Funders
Jimma University
Topics
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
Keywords
antihypertensive drugs, hypertension, blood pressure control, MMAS-8, comorbidities, alcohol consumption, combination antihypertensive therapy, associated factors, Jimma University Specialized Hospital, Ethiopia, hospital outpatients, cardiovascular risk reduction, drug costs, patient education, adverse drug reactions
MeSH terms
Assessment of Medication Adherence, Adult, Aged, Antihypertensive Agents, Cross-Sectional Studies, Ethiopia, Female, Hospitals, University, Humans, Hypertension, Male, Middle Aged, Drug Monitoring, Medication Adherence

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