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A comparison of two assessment tools used in overviews of systematic reviews: ROBIS versus AMSTAR-2
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BACKGROUND: AMSTAR-2 is a 16-item assessment tool to check the quality of a systematic review and establish whether the most important elements are reported. ROBIS is another assessment tool which was designed to evaluate the level of bias present within a systematic review. Our objective was to compare, contrast and establish both inter-rater reliability and usability of both tools as part of two overviews of systematic reviews. Strictly speaking, one tool assesses methodological quality (AMSTAR-2) and the other assesses risk of bias (ROBIS), but there is considerable overlap between the tools in terms of the signalling questions. METHODS: for weighted analysis). RESULTS: Thirty-one systematic reviews were included. For AMSTAR-2, the median agreement for all questions was 0.61. Eight of the 16 AMSTAR-2 questions had substantial agreement or higher (> 0.61). For ROBIS, the median agreement for all questions was also 0.61. Eleven of the 24 ROBIS questions had substantial agreement or higher. CONCLUSION: ROBIS is an effective tool for assessing risk of bias in systematic reviews and AMSTAR-2 is an effective tool at assessing quality. The median agreement between raters for both tools was identical (0.61). Reviews that included a meta-analysis were easier to rate with ROBIS; however, further developmental work could improve its use in reviews without a formal synthesis. AMSTAR-2 was more straightforward to use; however, more response options would be beneficial.
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“As AMSTAR 2 and the ROBIS tool 58 overlap in many sig naling questions, 37 the ROBIS tool was not used in this overview.”
From Acceptance and Commitment Therapy for Chronic Pain: An Overview of Systematic Reviews with Meta-Analysis of Randomized Clinical Trials (2024) · cites this paper as [37]
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Metadata
- Authors
- Perry, R., Whitmarsh, A., Leach, V., & Davies, P.
- Affiliations
- National Institute for Health and Care Research (GB)
- University Hospitals Bristol NHS Foundation Trust (GB)
- Corresponding author
- Perry, R.
- Venue
- Systematic Reviews
- Published
- 2021-10-25
- Volume
- 10
- Issue
- 1
- Pages
- 273-273
- ISSN
- 2046-4053 (ISSN-L)
- PMC
- PMC8543959
- OpenAlex
- W3173323133
- Cited by
- 130
- References
- 49
- Citations by year
- 2026: 22 · 2025: 24 · 2024: 33 · 2023: 37 · 2022: 13
- FWCI
- 0.86
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Systematic Reviews (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Bristol Research (University of Bristol) (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- University Hospitals Bristol NHS Foundation Trust
- National Institute for Health and Care Research
- National Institutes of Health
- National Institute for Health Research Applied Research Collaboration West
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Social Sciences › Sociology and Political Science › Delphi Technique in Research
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Reliability and Agreement in Measurement
- Keywords
- AMSTAR 2, ROBIS, overviews of systematic reviews, risk of bias, methodological quality assessment, inter-rater reliability, reporting quality, meta-analysis
- MeSH terms
- Systematic Reviews as Topic, Humans, Reproducibility of Results, Bias
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