The DOI matches its Crossref record; the references it cites are not checked yet.
A comprehensive review on bioactive peptides derived from milk and milk products of minor dairy species
Open accessAbstract
Abstract Milk from different species has been exploited for the isolation of various functional ingredients for decades. Irrespective of the source, milk is considered as a complete food, as it provides essential nutrients required by the human body. Proteins and their fractions are valuable sources of bioactive peptides that might exert a health beneficial role in the human body such as immune-modulation, antioxidant activity, ACE-inhibitory activity, anti-neoplastic, anti-microbial, etc. In milk, bioactive peptides may either be present in their natural form or released from their parental proteins due to enzymatic action. The increasing interest in bioactive peptides among researchers has lately augmented the exploration of minor dairy species such as sheep, goat, camel, mithun, mare, and donkey. Alternative to cow, milk from minor dairy species have also been proven to be healthier from infancy to older age owing to their higher digestibility and other nutritive components. Therefore, realizing the significance of milk from such species and incentivized interest towards the derivatization of bioactive peptides, the present review highlights the significant research achievements on bioactive peptides from milk and milk products of minor dairy species. Graphical abstract
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Two peptides generated from αS1-casein identified through the analysis in this work (Table 2), RPKHPIKHQ and RPKHPIKHQGLPQ, have been reported to exhibit antioxidant and ACE-inhibitory properties (Ardö et al., 2009, Guha et al., 2021).”
From Antioxidant and antihypertensive activity of Gouda cheese at different stages of ripening (2022) · cites this paper as Guha et al., 2021
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“One peptide, RPKHPIKHQGLPQE, has been reported to exhibit antioxidant properties (Ardö et al., 2009, Guha et al., 2021).”
From Antioxidant and antihypertensive activity of Gouda cheese at different stages of ripening (2022) · cites this paper as Guha et al., 2021
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Biological activity like antioxidant and ACE-inhibitory activity increases as proteolysis proceeds but only to a certain extent.”
From Antioxidant and antihypertensive activity of Gouda cheese at different stages of ripening (2022) · cites this paper as Guha et al., 2021
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“The presence of active peptides that are naturally formed in cheese depends on a delicate equilibrium between their formation and their degradation by the proteolytic systems involved in cheese ripening (Vargas-Bello-Pérez et al., 2019, Guha et al., 2021).”
From Antioxidant and antihypertensive activity of Gouda cheese at different stages of ripening (2022) · cites this paper as Guha et al., 2021
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
The citation lists are queued
They are fetched later and appear here then.
References 134 · Cited by 138
Research works printed but not linked: 3
- Elzahar, K., Sitohy, M., & Haertlé, T. (2004). Antimicrobial activity of ovine whey protein and their peptic hydrolysates. Milchwissenschaft, 59(11/12), 653–656 https://www.researchgate.net/publication/279541319. Accessed 5 Dec 2020.
- FAO (2013). MILK human nutrition dairy products. www.fao.org/.
- Mao, X. Y., Ren, F. Z., Li, Y. H., & Nan, Q. X. (2005). Growth-inhibiting activity of casein and its hydrolysate to tumor cells. Milchwissenschaft, 61(2), 127–130.
Metadata
- Authors
- Guha, S., Sharma, H., Deshwal, G. K., & Rao, P. S.
- Affiliations
- University of Nebraska–Lincoln (US)
- National Dairy Research Institute (IN)
- Venue
- Food Production, Processing and Nutrition
- Published
- 2021-01-11
- Volume
- 3
- Issue
- 1
- ISSN
- 2661-8974 (ISSN-L)
- OpenAlex
- W3165013764
- Cited by
- 138
- References
- 134
- Citations by year
- 2026: 22 · 2025: 31 · 2024: 35 · 2023: 23 · 2022: 23 · 2021: 4
- FWCI
- 6.67
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Food Production Processing and Nutrition (publishedVersion, cc-by)
- Lincoln (University of Nebraska) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Protein Hydrolysis and Bioactive Peptides
- Life Sciences › Agricultural and Biological Sciences › Food Science › Proteins in Food Systems
- Life Sciences › Immunology and Microbiology › Microbiology › Antimicrobial Peptides and Activities
- Keywords
- bioactive peptides, sheep milk, goat milk, camel milk, mare's milk, donkey milk, milk protein, ACE inhibitory activity, antioxidant activity, immunomodulation, antimicrobial peptides, dairy products, functional food ingredients
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A comprehensive review on bioactive peptides derived from milk and milk products of minor dairy species. https://app.cochat.ai/papers/10.1186/s43014-020-00045-7
- The paper
- Guha, S., Sharma, H., Deshwal, G. K., & Rao, P. S. (2021). A comprehensive review on bioactive peptides derived from milk and milk products of minor dairy species. Food Production, Processing and Nutrition. https://doi.org/10.1186/s43014-020-00045-7
