Immune system dysregulation during spaceflight: clinical risk for exploration-class missions
Abstract
Abstract Commentary on review by Gueguinou et al. on immune barriers and clinical risks to humans during prolonged, exploration-class space missions.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Differences in immune reactivity and susceptibility to infectious diseases between males and females are well described.
“Differences in immune reactivity and susceptibility to infectious diseases between males and females is well described (reviewed in [40], [41], [46], [47], [48]).”
From Hindlimb suspension and spe-like radiation impairs clearance of bacterial infections (2014) · cites this paper as [46]
The citation lists haven’t been fetched yet
References 15 · Cited by 108
- Authors
- Crucian, B., & Sams, C.
- Affiliations
- Johnson Space Center (US)
- Corresponding author
- Crucian, Brian
- Venue
- Journal of Leukocyte Biology
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-11-01
- Volume
- 86
- Issue
- 5
- Pages
- 1017-1018
- ISSN
- 0741-5400 (ISSN-L)
- 1938-3673
- OpenAlex
- W2067664087
- Cited by
- 108
- References
- 15
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 7 · 2023: 4 · 2022: 6 · 2021: 3 · 2020: 3 · 2019: 16 · 2018: 5 · 2017: 5 · 2016: 9 · 2015: 11 · 2014: 8 · 2013: 8 · 2012: 7
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Leukocyte Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Spaceflight effects on biology
- Life Sciences › Immunology and Microbiology › Immunology › Immunotoxicology and immune responses
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- immune dysregulation, spaceflight, clinical risk, immune barrier, astronaut health
- MeSH terms
- Acclimatization, Humans, Immune System Diseases, Risk Factors, Space Flight, Weightlessness
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
