Testosterone Therapy for Low Sexual Interest and Erectile Dysfunction in Men: a Controlled Study
Abstract
Summary: A double blind cross-over comparison of testosterone and placebo injection was carried out in two groups of men with normal circulating testosterone levels, 10 complaining principally of loss of sexual interest and 10 complaining principally of erectile failure. A significant increase in sexual interest was produced by testosterone in the first group. There was no effect on erectile function in either group. These results support previous findings from hypogonadal men that testosterone influences sexual interest but not erectile function, and indicate that increasing plasma testosterone can effect sexual interest even in men with pre-treatment testosterone levels within the normal range.
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In one small placebo-controlled study of eugonadal men with the primary complaint of low sexual desire, testosterone treatment produced a modest but significant increase in sexual desire.
“In one small placebo-controlled study of eugonadal men with the primary complaint of low sexual desire, O 'Carroll & Bancroft (1984) found a modest but significant increase in sexual desire with testosterone treatment.”
From The endocrinology of sexual arousal (2005) · cites this paper as O 'Carroll & Bancroft (1984)
In eugonadal men with erectile dysfunction, testosterone treatment produced no improvement in erections.
“O 'Carroll & Bancroft (1984) found no improvement in erections with testosterone treatment in eugonadal men with ED.”
From The endocrinology of sexual arousal (2005) · cites this paper as O 'Carroll & Bancroft (1984)
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References 16 · Cited by 188
- Authors
- O'Carroll, R., & Bancroft, J.
- Affiliations
- MRC Centre for Reproductive Health (GB)
- Corresponding author
- Bancroft, John
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 1984-08
- Volume
- 145
- Issue
- 2
- Pages
- 146-151
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2106032422
- Cited by
- 188
- References
- 16
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 3 · 2018: 1 · 2017: 4 · 2016: 4 · 2015: 2 · 2014: 4 · 2013: 2 · 2012: 3
- FWCI
- 3.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Keywords
- testosterone replacement therapy, testosterone injection, erectile dysfunction, male sexual dysfunction, hypogonadism, sexual desire
- MeSH terms
- Adult, Clinical Trials as Topic, Double-Blind Method, Drug Combinations, Female, Humans, Male, Middle Aged, Sexual Dysfunction, Physiological, Sex Hormone-Binding Globulin, Testosterone
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